Results 91 to 100 of about 19,019 (225)
Natural sciences and chess: A romantic relationship missing from higher education curricula. [PDF]
Uskoković V.
europepmc +1 more source
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza +19 more
wiley +1 more source
BIRTHING FROM WITHIN: Nature, Technology, and Self-Making in Silicon Valley Childbearing. [PDF]
Ford A.
europepmc +1 more source
Networked Religion: Metaphysical Redemption or Eternal Regret? [PDF]
McLaren P.
europepmc +1 more source
From Sapore to Sapere : the gustatory perception of elsewhere in Calvino’s ‘Under the Jaguar Sun’ [PDF]
This essay seeks to show how the gustatory perception of “elsewhere” intensifies human sapience of not only the exotic Other, but also of the self. In other words, it argues that Calvino’s desire to communicate with flavours in ‘Under the Jaguar Sun’ can
Satarupa Sinha, Roy
core
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu +10 more
wiley +1 more source
The Legitimate Route to the Scientific Truth - The Gondor Principle [PDF]
We leave in a beautiful and uniform world, a world where everything probable is possible. Since the epic theory of relativity many scientists have embarked in a pursuit of astonishing theoretical fantasies, abandoning the prudent and logical path to ...
Krecz, Joseph
core
Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley +1 more source
Polyelectrolyte Design Principles for Electrophoretic Drug Delivery
Structure–property–function mapping of polyelectrolytes reveals how composition and nanoscale order control on‐demand electrophoretic drug transport. Charge density quantified under implant‐relevant conditions shows that encapsulation limits swelling, enabling high effective charge density.
Helena Saarela Unemo +8 more
wiley +1 more source
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li +10 more
wiley +1 more source

