Results 61 to 70 of about 27,634 (263)
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
In die Skriflig, 2019 This article considers equality as a constitutional value from a Christian perspective. In view of the current questions about equality in the emerging post-secular paradigm, the specific aim of this study is to ascertain the relevance of Galatians 3:28 ...
Jakobus M. Vorster
doaj +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
RUDN Journal of Law, 2016 The article considers the correlation of general principles of law, the principles of international law and the principles of aw of international organizations.
Aleksandra Andreevna Dorskaya
doaj
Part-time criminal proceedings in the context of Justice in the Republic of Belarus
Проблеми Законності, 2019 In recent years, the Criminal Procedure Code of the Republic of Belarus (hereinafter referred to as the Code of Criminal Procedure) has been amended to simplify and speed up judicial procedures.
Игорь Владимирович Данько
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Using Sadrai Model to Interpret the Principle of Equality in Human Rights [PDF]
حکمت صدرایی, 2018 There aretwodiscoursesconcerning human rights: contractual and un-contractual. Equality of law and equality before lawis based onthe equality of the deserving; but, in un-contractual discourse, the equality of the deserving isan objective thing and ...
Abdollah Salavati, Shahnaz Shayanfar
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Perspectives on Federalism, 2017 After a discussion of the impact of the principle of equality, entrenched in the Charters approved in Canada since the 1867 British North American Act, this essay then focuses on the related Supreme Court’s adjudications. A brief analysis of the case-law
Scotti Valentina Rita
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Intelligent Tutoring Systems for Adult Learning in STEM Disciplines
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley +1 more source