Results 71 to 80 of about 2,972 (267)

The FOXC2‐LAMA4 Axis Orchestrates Vasculogenic Mimicry and Immunosuppressive Niche Formation to Drive Metastatic Cascade in Renal Cell Carcinoma

Advanced Science, EarlyView.
Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao, Tong Xu, Chengyuan Wang, Chenyuan Wang, Junfeng Xie, Rui Zheng, Ke Wang, Xingzuo Jiang, Zewei Hu, Hongwei Jing, Lin Li, Tao Liu   +11 more
wiley   +1 more source

The principle of legality and the provision “the judge is subject to the law” in the context of the doctrine of the development of law contra legem

Правоприменение
The research subject. This study focuses on the correlation between the doctrine of development of law contra legem and the principle of legality, with a specific emphasis on the position that “judge submits to the law”.The purpose of the research.
A. S. Ghambaryan
doaj   +1 more source

Formulating Criminal Liabilities Regarding Online Prostitution

Lentera Hukum, 2019
This study aims to obtain similarities and differences regarding legal formulation in online prostitution. Hitherto, prostitution has remained to exist in Indonesian society.
Trio Angga Laksana, Y.A. Triana Ohoiwutun, Fanny Tanuwijaya   +2 more
doaj   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Soft Robotics and Advanced Technologies for Minimally Invasive Bioprinting: The Future of Internal Organ Repair

Advanced Science, EarlyView.
This review examines the evolution of bioprinting toward minimally invasive in situ strategies for internal organ regeneration. It defines the technological roadmap from handheld systems to advanced minimally invasive bioprinting platforms, positioning soft robotics as a core enabler.
Duc Tu Vu, Nhu An Phan, Sy Trung Ngo, Minh Tri Phan, Thanh‐An Truong, Chi Cong Nguyen, Phuoc Thien Phan, Hoang‐Phuong Phan, Thanh Nho Do, Mai Thanh Thai   +9 more
wiley   +1 more source

CONCEPTION OF NORMATIVE LEGAL ACTS LEGALITY AND ITS REFLECTION IN REGIONAL LEGISLATION

Russian Journal of Economics and Law, 2013
Objective: to view the application of legality principle in normative legal acts of regional legislation. Methods: dialectical method of cognition. Results: Basing on theoretical analysis of the presented definitions of “legality” the conclusion is made ...
A. G. Galimov
doaj  

Discovering Interpretable Semantics from Radio Signals for Contactless Cardiac Monitoring

Advanced Science, EarlyView.
This study presents a semantic representation framework for clinically interpretable cardiac monitoring from contactless radio signals. It formulates radio semantic learning as an information‐bottleneck problem and approximates the objective via intra‐modal compression and cross‐modal alignment, structuring radio measurements into meaningful semantic ...
Jinbo Chen, Haoyu Wang, Guixin Xu, Yuqin Yuan, Xinmeng Cai, Zhengwu Wei, Dongheng Zhang, Qibin Sun, Tianwei Zhang, Cuntai Guan, Yan Chen   +10 more
wiley   +1 more source

The Judicial Control of the Administrative Acts Legality in Community Law. Exempted Acts of the Community Judicial Control

Acta Universitatis Danubius: Administratio, 2010
The present paper has as its main objective to present the role played by the legality principle for the rule of law as well as to analyse the signification of legality control of administrativeacts in the context of European Union law, and to present ...
Denisa Loredana BICA, Andreea-Diana PAPA
doaj  

REKONSTRUKSI ASAS LEGALITAS DALAM HUKUM PIDANA BERDASARKAN PRINSIP KEADILAN

Refleksi Hukum, 2016
Abstrak Salah satu prinsip penting dalam hukum pidana terdapat di dalam asas legalitas yang menyatakan bahwa, “tidak ada suatu perbuatan yang dapat dipidana kecuali atas kekuatan undang-undang pidana yang ada sebelum perbuatan itu dilakukan.” Asas ...
Fransiskus Saverius Nurdin
doaj   +1 more source

Nanozymes for Liver Disease Therapy: Advances in Catalytic Activity, Targeting Strategies, and Clinical Translation

Advanced Science, EarlyView.
Nanozymes, as enzyme‐mimicking nanomaterials, exhibit unique catalytic properties for the treatment of liver diseases. By regulating redox homeostasis, modulating immune responses, and enabling targeted delivery, nanozymes overcome the limitations of natural enzymes.
Xiandi Meng, Ge Zhu, Siyu Sun, Wenbo Yao, Yuning Zhang, Yong‐Guang Yang, Tianmeng Sun   +6 more
wiley   +1 more source