Results 51 to 60 of about 178,872,919 (296)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

The late discovery of adoptive and donor insemination offspring status : ethical implications for conceptual understandings of the ‘best interests of the child’ principle\ud [PDF]

open access: yes, 2012
Late discovery is a term used to describe the experience of discovering the truth of one’s genetic origins as an adult. Following discovery, late discoverers face a lack of recognition and acknowledgment of their concerns from family, friends, community ...
Riley, Helen J.
core  

’n Regsteoretiese en funks ionele perspektief op die beste belange van die (minderjarige) kind

open access: yesKoers : Bulletin for Christian Scholarship, 1991
In most modern legal systems the principle of the child’s best interests is held to be the panacea for adjudication in cases of interference within an intact family unit or remediation whenever the family is split apart.
G.H. Fick
doaj   +1 more source

PROCEDURAL RIGHTS OF A CHILD IN CIVIL LITIGATION IN THE LIGHT OF THE BEST INTERESTS OF THE CHILD PRINCIPLE

open access: yesBulletin of Taras Shevchenko National University of Kyiv. Legal Studie, 2022
The article considers the concept of "best interests of the child" and the problems of its implementation in the current legislation of Ukraine. The current legislation of Ukraine is analysed concerning the adequacy of the existing procedural rights of the child in civil proceedings to provide a minor and a minor child the opportunity to express their ...
openaire   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

THE BEST INTERESTS OF THE CHILD FROM AN ADULT PERSPECTIVE (A Case Study on Child Marriage Dispensation Cases at the Sukadana Religious Court)

open access: yesIstinbath
This study examines how the child's best interests principle is applied in child marriage dispensation cases at the Sukadana Religious Court, emphasizing the contrasting viewpoints of applicants (parents or guardians) and judges.
Muhammad Nur Fathoni   +2 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

The Best Interests of the Child Principle at the Intersection of Private International Law and Human Rights

open access: yes, 2019
This contribution aims to investigate the systemic role of the Best Interests of the Child principle in contemporary international family law. For private international law and international human rights law, the Principle, as expression of a progressive
Distefano M.
core   +1 more source

The Best Interests of the Child and the Challenge of Digital Re-Victimization in Child Sexual Abuse Material (CSAM) Cases

open access: yesSocial Sciences
Child Sexual Abuse Material (CSAM) constitutes one of the most serious forms of child sexual abuse in the digital environment, causing not only primary harm at the moment of abuse but also prolonged and repeated victimization due to the continued storage,
Inga Kudeikina
doaj   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

open access: yesFEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court   +3 more
wiley   +1 more source

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