Results 111 to 120 of about 15,848,411 (295)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Contrastive learning method for leak detection in water distribution networks

open access: yesnpj Clean Water
Detecting and mitigating leaks in water distribution networks are vital for water conservation. Machine-learning-based (ML) acoustic leak detection models were introduced as effective alternatives for leak management.
Rongsheng Liu, Tarek Zayed, Rui Xiao
doaj   +1 more source

The reals and the reals

open access: yesGeneral Topology and its Applications, 1978
Bentley, H.L., Herrlich, H.
openaire   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A comprehensive review of sustainable materials and toolpath optimization in 3D concrete printing

open access: yesnpj Materials Sustainability
The construction sector has experienced remarkable advancements in recent years, driven by the demand for sustainable and efficient building practices. Among these advancements, 3D concrete printing has emerged as a highly promising technology that holds
Zicheng Zhuang   +5 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Real-Time Forecasts of the Real Price of Oil [PDF]

open access: yes
We construct a monthly real-time data set consisting of vintages for 1991.1-2010.12 that is suitable for generating forecasts of the real price of oil from a variety of models.
Christiane Baumeister, Lutz Kilian
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Advancing the analysis of water pipe failures: a probabilistic framework for identifying significant factors

open access: yesScientific Reports
The failure of water pipes in Water Distribution Networks (WDNs) is associated with environmental, economic, and social consequences. It is essential to mitigate these failures by analyzing the historical data of WDNs.
Muhammad Muddassir   +3 more
doaj   +1 more source

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