Results 11 to 20 of about 639,780 (330)
ACS Chemical Biology, 2014 Increased signaling by the small G protein Ras is found in many human cancers and is often caused by direct mutation of this protein. Hence, small-molecule attenuation of pathological Ras activity is of utmost interest in oncology. However, despite nearly three decades of intense drug discovery efforts, no clinically viable option for Ras inhibition ...
Milroy, L.G., Ottmann, C.
openaire +3 more sources
Molecular Oncology, 2020 Pancreatic ductal adenocarcinoma (PDAC) is predicted to become the second leading cause of cancer‐related deaths in the United States by 2020, due in part to innate resistance to widely used chemotherapeutic agents and limited knowledge about key ...
Chun‐Hao Pan +14 more
doaj +1 more source
Frontiers in Neurology, 2022 Recovery of consciousness after traumatic brain injury (TBI) is heterogeneous and difficult to predict. Structures such as the thalamus and prefrontal cortex are thought to be important in facilitating consciousness.
Megan E. Cosgrove +12 more
doaj +1 more source
Suitable classification of mortars from ancient roman and renaissance frescoes using thermal analysis and chemometrics [PDF]
, 2015 Background Literature on mortars has mainly focused on the identification and characterization of their components in order to assign them to a specific historical period, after accurate classification.
Campanella, Luigi +4 more
core +1 more source
Chemie Ingenieur Technik, EarlyView., 2023 Let us consider an alternative perspective on climate change: The sum of solar radiation and heat generated by human activity result in a net energy input of 1.96 times that of the Sun on the Earth's surface. The expanding global population is expected to exacerbate this issue. Potential solutions are proposed, including replacement and heat recycling.
Martin Bertau, Gerald Steiner
wiley +1 more source
Вестник музыкальной науки, 2015 В статье рассматриваются исторические параллели развития и взаимодействие русской и английской музыкальных культур. Несмотря на географическую и политическую удаленность России и Англии, они имеют много общего.
Миклухо, Елена Олеговна
doaj +1 more source
Reduced cerebellar cortical thickness in World Trade Center responders with cognitive impairment
Translational Psychiatry, 2022 Prior research has demonstrated high levels of cognitive and physical functional impairments in World Trade Center (WTC) responders. A follow-up neuroimaging study identified changes to white matter connectivity within the cerebellum in responders with ...
Sean A. P. Clouston +12 more
doaj +1 more source
, 2018 Sound, basically characterized as air in motion since ancient Greece, has been at the core of the theories of many philosophers, as well as musicians, poets, scientists, and theologians.
Gutiérrez Cajaraville, Carlos
core +2 more sources
Religions, 2022 This article explores the surprisingly positive attitude towards pilgrimage and saints that developed within mainstream Lutheran faith during the Seventeenth Century.
Martin Wangsgaard Jürgensen
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ImmCellFie: A user-friendly web-based platform to infer metabolic function from omics data
STAR Protocols, 2023 Summary: Understanding cellular metabolism is important across biotechnology and biomedical research and has critical implications in a broad range of normal and pathological conditions. Here, we introduce the user-friendly web-based platform ImmCellFie,
Helen O. Masson +13 more
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