Results 21 to 30 of about 3,618,762 (343)

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Clinical and Epidemiological Features of Allergies in Schoolchildren of the Chechen Republic: Results of an Epidemiological Study

Педиатрическая фармакология, 2023
Background. One of the topical issues of modern medicine is the widespread increase in the incidence of allergic pathology. Objective. The aim of the study is to investigate clinical and epidemiological features of allergies in schoolchildren of the ...
Aset Kh. Ibisheva, Saihat A. Shamsadova, Leyla S. Namazova-Baranova   +2 more
doaj   +1 more source

Clinical Practice Guideline for Primary Liver Cancer(2024 Edition)

Xiehe Yixue Zazhi
Primary liver cancer is one of the common malignant tumors in China. According to the cancer statistics report in China for the year 2022, the incidence and mortality rates of primary liver cancer in our country rank 5th and 2nd, with 367 700 new cases ...
Department of Medical Administration, National Health Commission of the People's Republic of China
doaj   +1 more source

Price effects of VAT introduction in Croatia [PDF]

, 1997
This Occasional Paper is based on the research project “Analysis of the fiscal system of the Republic of Croatia at the introduction of value added tax” undertaken by the Institute of Public Finance and financed by the Ministry of Finance of the Republic
Dalic, Martina
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Uneven transmission of traditional knowledge and skills in a changing wildmeat system: Yangambi, Democratic Republic of Congo [PDF]

, 2023
Samuel Shephard, Jonas Muhindo, Jonas Nyumu, Emmanuela Mbangale, Sagesse Nziavake, Paolo Cerutti, Nathalie van Vliet   +6 more
openalex   +1 more source

The behaviour of political parties and MPs in the parliaments of the Weimar Republic [PDF]

, 2011
Copyright @ 2012 The Authors. This is the author's accepted manuscript. The final published article is available from the link below.Analysing the roll-call votes of the MPs of the Weimar Republic we find: (1) that party competition in the Weimar ...
Berg-Schlosser Dirk, Berman Sheri, Carrubba Clifford J., Clinton Joshua, Downs Anthony M., Hansen Martin Ejnar, Hix Simon, Hix Simon, Hug Simon, Jackman Simon, Jones Larry Eugene, Jones Larry Eugene, Kolb Eberhard, Laver Michael, Lehmann Sibylle H., Lepsius M. Rainer, Lieberman Ben, Lipset Seymour M., Loewenberg Gerhard, Longerich Peter, Markmann Heinz, McLean Iain, Mergel Thomas, Mergel Thomas, Morgenstern Scott, Myerson Roger B., Müller Wolfgang C., Nagel Jack H., Peukert Detlev, Poole Keith T., Pyta Wolfgang, Rice Stuart A., Robertson David, Rosenthal Howard, Saalfeld Thomas, Schonhardt-Bailey Cheryl, Schröder Wilhelm Heinz, Schulze Hagen, Schönhoven Klaus, Schönhoven Klaus, Sieberer Ulrich, Spirling Arthur, Spirling Arthur, van Riel Arthur, Voeten Eric   +44 more
core   +1 more source