Results 51 to 60 of about 4,219,336 (366)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Reassembling the Republic of Letters - A Linked Data Approach
Digital Humanities in the Nordic Countries Conference, 2018 Between 1500 and 1800, a revolution in postal communication allowed ordinary men and women to scatter letters across and beyond Europe. This exchange helped knit together what contemporaries called the respublica litteraria, or Republic of Letters, a ...
J. Tuominen +5 more
semanticscholar +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Highly qualified in the Czech Republic
Journal of International Studies, 2017 The paper aims to analyse the current situation of the highly qualified in the Czech Republic applying the ISCO qualification. Previous studies suggest that educational attainment has an important impact on labour market performance and national ...
Renata Čuhlová, Zuzana Potužáková
doaj +1 more source
The Roles of the Supreme Court of the Republic Indonesia in Enforcement of International Arbitral Awards in Indonesia [PDF]
, 2013 Indonesia has been being a member of the 1958 New York Convention since 1981, namely upon issuance of the Presidential Decree No. 34 of 1981. Prior to taking into force of the Regulation of the Supreme Court of the Republic of Indonesia No.
Hikmah, M. (Mutiara)
core
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
OECD/G20 Base Erosion and Profit Shifting Project, 2020 The Dominican Republic has enjoyed a prosperous decade with high growth, low inflation, a relatively strong external position and significant gains in poverty reduction.
semanticscholar +1 more source
The Structure of Consumer Basket in the Czech Republic and Slovak Republic [PDF]
, 2014 Purpose of the article: Nowadays, consumer behaviour is still at the centre of attention of many researchers. The consumer basket belongs among important economic characteristics, which determine the economic level of each country.
Gottwald, Radim
core
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
The electoral system in the Republic of Macedonia [PDF]
, 2015 Initially the paper will treat the history of pluralist elections held in Macedonia since its independence and the establishment of a democratic system after 1991 and throughout the democratic transition until today.
Maksuti, Mersim
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