Results 41 to 50 of about 552,218 (310)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
From Invisibility towards Justice: The march of the marginalized citizens of Mumbai”
Miscellanea Geographica: Regional Studies on DevelopmentMumbai, like Marozia is a city where for many the living conditions are like those described by Calvino for rats but who hope to fly like swallows. It’s a city where many come to eke out a livelihood, increasingly difficult in rural areas.
Desai Manisha
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Faṣlnāmah-i Pizhūhish-i Huqūq-i ̒Umūmī, 2021 Cities contain more than half of the world's population. Urban sprawl and environmental degradation would cause irreparable damage to the cities and their citizens. A considerable number of the urban population suffer from the lack of human rights in the cities.
sanaz kamyarrad +2 more
openaire +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Introduction: Locating right to the city in the Global South
, 2013 link_to_subscribed_fulltex
Samara, Tony Roshan +2 more
core +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
تحقيقات جغرافيايی, 2018 One of the dimensions of democracy is the homological, responsive and welcoming spaces. Power in space includes a variety of features and different aspects.
Maryam farahzad +3 more
doaj
Children’s right to the city : The emergence of youth councils in the United States
, 2017 The United Nations Convention on the Rights of the Child (CRC) spells out many rights, including the right to participate in decision-making. Within an urban context, a child’s ‘right to the city’ includes the opportunity to participate in local ...
Cushing, Debra Flanders +1 more
core +1 more source