Results 21 to 30 of about 126,960,388 (221)

The investigation of the origins of humorous nicknames given to farmers along the Greater Letaba River [PDF]

, 2014
Thesis (M. A. (African Languages)) --University of Limpopo, 2014This study analyse Nicknames Given to farm owners along the Great Letaba River .The study indicates that names are some of the most important things in people’s lives.
Malungani, M. M.
core  

THE ASSOCIATION-DERIVATION STRATEGIES OF A LANGUAGE GAME IN THE NICKNAMES OF MODERN YOUTH

, 2019
In article the possibilities of use of reception of a language (onomastichesky) language game for creation of nicknames among young people are considered; the associative and derivational strategy of a language game from the point of view of a world ...

core   +1 more source

PFKFB4 Deubiquitination by USP10 Enhances Fumarate Metabolism to Orchestrate the KDM1A/Rad51 Axis and Confer Radioresistance in Lung Cancer

Advanced Science, EarlyView.
USP10 binds to and stabilizes PFKFB4, enhancing glycolytic ATP production, which activates the urea cycle and elevates fumarate. This inhibits histone demethylase KDM1A, leading to increased H3K4me1 enrichment at the Rad51 promoter and direct activation of Rad51 transcription, which confers lung cancer radioresistance. The PFKFB4 inhibitor 5MPN targets
Yunshang Chen, Zilong Wu, Yongqiang Yang, Ruoxin Fang, Huichan Xue, Rui Zhou, Gang Wu, Xiaohua Jie   +7 more
wiley   +1 more source

Innovative artifacts of the unofficial anthroponymicon of Ukrainian politics in the contemporary metamodern discourse

Вісник Харківського національного університету імені В. Н. Каразіна. Серія Філологія. Vìsnik Harkìvsʹkogo nacìonalʹnogo unìversitetu ìmenì V.N. Karazìna. Serìâ Fìlologìâ.
The article is devoted to the study of current trends in unofficial naming, especially neogenic derivative processes. The author aims to explore innovative artifacts of the unofficial anthroponymicon of Ukrainian politics from the perspective of ...
Kateryna Diukar
doaj   +1 more source

Nanoparticle‐Mediated TIPE1 mRNA Delivery Enhances Paclitaxel Sensitivity in Triple‐Negative Breast Cancer by Modulating RAB7A Ubiquitination‐Associated Stability and Autophagy

Advanced Science, EarlyView.
TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu, Qishuai Chen, Yan Ma, Yang Liu, Xianing Dong, Wenjuan Wei, Jianxin Du, Shusheng Qiu, Maojin Tian, Peiqing Zhao   +9 more
wiley   +1 more source

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin, Wenjing Zhao, Lei Wang, Jianing Wang, Keying Zhao, Dan Luo, Yifei Wang, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Xiaoyan Li, Bing Chen, Lijuan Wang, Yiran Liang, Qifeng Yang   +17 more
wiley   +1 more source

THE CONCEPT OF THE PROPHET IN BUILDING DOMESTIC HARMONY

Hakam: Jurnal Kajian Hukum Islam dan Hukum Ekonomi Islam
This study analyzes the Prophetic concept of building household harmony through family-related hadiths found in Sahih Bukhari and Sahih Muslim. The research is motivated by Indonesia’s high divorce rate in 2023, which reached 408,347 cases, with 251,828 ...
Muhammad Fathur Rahcman Imanda, Winning Son Ashari   +1 more
doaj   +1 more source

OTUD6A‐Mediated Deubiquitination of PRDX1 Protects Against Oral Ulcer by Restoring Mitochondrial Function

Advanced Science, EarlyView.
In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun, Ruiwei Jia, Xingbei Pan, Rui Huang, Jiahong Chen, Ziyi Yao, Lei Yin, Jun Ma, Hongjieliang Wang, Xinyu Huang, Yilin Ma, Yifan Ping, Yuanyuan Chen, Huining Wang, Shengbin Huang, Guang Liang   +15 more
wiley   +1 more source

USP30‐Mediated Deubiquitination of PEX5 Suppresses Pexophagy to Drive Tubular Injury in Diabetic Kidney Disease

Advanced Science, EarlyView.
USP30 accumulation in diabetic renal tubular epithelial cells deubiquitinates PEX5, suppresses pexophagy, and drives dysfunctional peroxisome accumulation and tubular injury. USP30 depletion restores PEX5 ubiquitination and pexophagy, improves peroxisomal function, and alleviates tubular damage, highlighting USP30 as a therapeutic target in diabetic ...
Jia Li, Chaoyang Hua, Guangpu Li, Furong Zhai, Jingjing Ren, Shaokang Pan, Qi Feng, Jianguo Wen, Dongwei Liu, Zhangsuo Liu, Jiayu Duan   +10 more
wiley   +1 more source

Generation and Attribution of Nicknames among Secondary School Students: Indices of Linguistic Creativity [PDF]

, 2015
The subject of naming is a universal one (Ajileye and Ajileye, 2003) but it has different importance in different clans. The motivation for this study is hinged on the extent to which nicknames are generated and attributed among secondary school students
Clement Tayo, ABEGUNDE,, Damilare Daniel, ATOLAGBE,, Taiye, MORONFOYE, Olayiwola   +2 more
core   +1 more source