Results 51 to 60 of about 11,921 (295)

Disruption of the SNRPF–DDX24–E2F4 Feedback Loop Uncouples Splicing and Transcriptional Regulation to Suppress Ovarian Cancer Progression

open access: yesAdvanced Science, EarlyView.
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li   +4 more
wiley   +1 more source

The Shanghai Cooperation Organization: An Historical Perspective

open access: yes, 2015
Publié sur le portail http://www.e - ir.info/2015/09/17/the - shanghai - cooperation - organization - an - historical ...
Depeyrot, Georges
core   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

open access: yesAdvanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa   +8 more
wiley   +1 more source

The Shanghai Cooperation Organization amidst the Rising International Tensions

open access: yesJournal of Eurasian Studies
The Shanghai Cooperation Organization (SCO), established over two decades ago, stands as one of the most prominent international entities within the non-Western geopolitical sphere.
Alexander Lukin   +3 more
doaj   +1 more source

Pakistan and Regional Cooperation Organizations: Towards a Futuristic Approach

open access: yesPolicy Perspectives, 2017
Pakistan is member of Economic Cooperation Organization (ECO) and South Asian Association for Regional Cooperation (SAARC) for past more than three decades.
Irfan Shahzad
doaj   +1 more source

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

open access: yesAdvanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang   +10 more
wiley   +1 more source

The Shanghai Cooperation Organization after Enlargement: New Challenges and Prospects

open access: yesВестник Московского Университета. Серия XXV: Международные отношения и мировая политика, 2020
The paper examines new challenges that confront the Shanghai Cooperation Organization (SCO) after India and Pakistan have joined it as full-fledged members. This enlargement of the SCO implies a considerable increase in its political and economic weight,
D. V. Efremenko
doaj  

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

open access: yesAdvanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu   +8 more
wiley   +1 more source

China and Central Asia: the Role of the Shanghai Cooperation Organization (SCO)

open access: yesThe Mongolian Journal of International Affairs, 2013
The Mongolian Journal of International Affairs; Number 11, 2004, Page 129-151 DOI: http://dx.doi.org/10.5564/mjia.v0i11 ...
Richard Hu
doaj   +1 more source

A Dual‐Functional Biohybrid Nanorobot to Synergistically Eradicate Biofilm and Degrade Antibiotic Resistance Genes

open access: yesAdvanced Science, EarlyView.
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang   +9 more
wiley   +1 more source

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