Results 81 to 90 of about 259,009 (257)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

The effect of optimum launching on the reduction of offshore jacket weight

نشریه مهندسی دریا, 2016
Launching method is commonly applied for installation of heavy template (jacket) platforms. One of the important phases in design and construction of offshore platforms is launching condition. This will insure the safty of the procedure and will optimize
ali zakeri, ahmad shanehsazzadeh
doaj  

Simulated surgery of single-port robotic transanal total mesorectal excision: a case study

结直肠肛门外科
Surgical simulators offer surgeons the opportunity to practice surgical procedures in a simulated environment, while single-port robotic surgical system provide a platform with exceptional operational flexibility and precision.
He Kuan, Xu Zhou, Shen Haode, Zheng Huichao, Du Jing, Xu Kun, Tong Weidong, Wu Yi, Li Fan   +8 more
doaj   +1 more source

Identification of Acoustic Characteristic Parameters and Improvement of Sound Absorption Performance for Porous Metal

Metals, 2020
Porous metal is widely used in the fields of sound absorption and noise reduction, and it is a critical procedure to identify acoustic characteristic parameters and to improve sound absorption performances.
Xiaocui Yang, Xinmin Shen, Haiqin Duan, Xiaonan Zhang, Qin Yin   +4 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Transductive Radar Clutter Segmentation Network for Ionospheric Inhomogeneity Clutter Suppression

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
The ionosphere turbulent motions, detected by radar systems, result in a complex form of ionospheric inhomogeneity clutter. In this article, we introduce transductive radar clutter segmentation network (TRCS-Net), a deep unfolding network architecture ...
Yuanbiao Li, Lei Yu, Yinsheng Wei
doaj   +1 more source

Mapping atomistic to coarse-grained polymer models using automatic simplex optimization to fit structural properties

, 2000
We develop coarse-grained force fields for poly (vinyl alcohol) and poly (acrylic acid) oligomers. In both cases, one monomer is mapped onto a coarse-grained bead.
Meyer, Hendrik, Mueller-Plathe, Florian, Reith, Dirk   +2 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Application of digital twins for simulation based tailoring of laser induced graphene

Scientific Reports
In the era of man–machine interfaces, digital twins stand as a key technology, offering virtual representations of real-world objects, processes, and systems through computational models.
José Carlos Santos-Ceballos, Foad Salehnia, Alfonso Romero, Xavier Vilanova   +3 more
doaj   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source