Results 91 to 100 of about 15,109,518 (303)
NINETIETH ANNUAL REPORT OF THE SOUTH CAROLINA STATE HOSPITAL FOR THE INSANE FOR THE YEAR 1913 [PDF]
The South Carolina State Hospital, first named the South Carolina Lunatic Asylum, was completed in 1828 in Columbia as one of the first asylums in the county built expressly for the mentally ill and funded by the state government.
South Carolina State Hospital for the Insane
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In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Office of the State Auditor FY 2003-2004 Accountability Report [PDF]
The South Carolina Office of the State Auditor reports to the Office of State Budget its annual accountability report that includes an executive summary, organizational profile including leadership system, program descriptions and budgets, and program ...
South Carolina Office of the State Auditor
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Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source

