Results 131 to 140 of about 15,109,518 (303)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Office of the State Auditor FY 2011-2012 Accountability Report

, 2011
The South Carolina Office of the State Auditor reports to the Office of State Budget its annual accountability report that includes an executive summary, organizational profile including leadership system, program descriptions and budgets, and program ...
South Carolina Office of the State Auditor
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Eighty-Second Annual Report OF THE South Carolina State Hospital for the Insane FOR THE Year 1905 [PDF]

, 1906
The South Carolina State Hospital, first named the South Carolina Lunatic Asylum, was completed in 1828 in Columbia as one of the first asylums in the county built expressly for the mentally ill and funded by the state government.
South Carolina State Hospital for the Insane
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Eighty-Third Annual Report of the South Carolina State Hospital for the Insane For the Year Nineteen Hundred and Six [PDF]

, 1907
The South Carolina State Hospital, first named the South Carolina Lunatic Asylum, was completed in 1828 in Columbia as one of the first asylums in the county built expressly for the mentally ill and funded by the state government.
South Carolina State Hospital for the Insane
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Other title: Report of the Connecticut state parks and forests; Other title: Some volumes reissued with cover title: Connecticut state parks and forests,

Biennial; Began with June 30, 1922; ceased with June 30, 1930.; "Printed in accordance with statute."; Has separately titled section: Report of the State Forester.; Issued also as State of Connecticut Public document no ...
Connecticut. State Park and Forest Commission.
core  

Office of the State Treasurer Annual Accountability Report 94-95

, 1995
The South Carolina Office of the State Treasurer reports to the Office of State Budget its annual accountability report that includes an executive summary, organizational profile including leadership system, program descriptions and budgets, and program ...
South Carolina Office of the State Treasurer
core  

REPORT OF THE STATE TREASURER OF SOUTH CAROLINA FOR THE FISCAL YEAR 1916 [PDF]

, 1916
The South Carolina Office of the State Treasurer reports to the Office of State Budget its annual accountability report that includes an executive summary, organizational profile including leadership system, program descriptions and budgets, and program ...
South Carolina Office of the State Treasurer
core