Results 201 to 210 of about 15,109,518 (303)

South Carolina State Library Presents ... National Parks and Recreation Month

This document highlights the partnership between the South Carolina State Library and South Carolina Parks, Recreation and Tourism to encourage patrons to take advantage of public spaces, specifically state parks, and reap the benefits of spending more ...
South Carolina State Library
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Notes from the Field: Initial Public Health Response to a Measles Outbreak in a Close-Knit West Texas Community - January-February 2025. [PDF]

MMWR Morb Mortal Wkly Rep
Crisp CA, Milton S, Lutz CS, Northcott K, McClaran K, Hernandez C, Almas S, Holbrooks Z, Wells K, Sajewski E, Texas 2025 Measles Outbreak Response Team, CDC Epi-Aid Measles Response Team, Morrison A, Schroeder C, Nolen M, Gonzales J, Martinez D, Rai S, Shetty V, Shuford JA.   +19 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Real-Time Monitoring of Excited-State Ring-Puckering Process in BODIPY Molecule Using Ultrafast Spectroscopy. [PDF]

Chemphyschem
Sen A, Mora AK, Nath S.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Cross-Sectional and Longitudinal Comparison of Commonly Used Screening Tools for Bipolar Disorders. [PDF]

Bipolar Disord
Tröger A, Zeng Y, Richardson T, Palmer-Cooper E, Young AH, Strawbridge R.   +5 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Changes in the Education-Health Gradient Within U.S. States, 1993-2019. [PDF]

Popul Res Policy Rev
Montez JK, Gutin I, Finan JM, Zajacova A, Landes S.   +4 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source