Results 41 to 50 of about 948,354 (262)

Decision support system with a Telegram bot and machine learning methods for the real estate market

Вестник Пермского университета: Серия Экономика
Introduction. The problem of managing investments in residential real estate as a tool for generating income is considered; an investment option with mortgage lending and no additional funds is proposed.
Victor Victor, Tatiana Zolotova
doaj   +1 more source

Institutional control of the financial and business operations of state institutions: practical data in the area of public healthcare and trends in its development

Вестник Воронежского государственного университета: Серия экономика и управление, 2021
Subject. The organisational and methodological aspects of the institutional control of financial and business operations and other types of institutional control carried out by executive authorities in relation to their subordinate institutions ...
Сергей Владимирович Головин
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Methods of clinical assessment from the “Clinical Recommendations” resource of the Ministry of Healthcare of Russia: a systematic review

Фармакоэкономика, 2018
One of the key elements of medical care is the assessment of the patient’s condition, which allows making a diagnosis and evaluating the patient’s health status, the severity of the disease  and the prognosis of its outcome.
V. M. Vatolin, O. A. Sukhorukikh, Zh. A. Galeeva, D. V. Lukyantseva, O. O. Buzuverova, O. V. Kirsanova, E. M. Murtazina, D. G. Ilyukhin, L. S. Shubina   +8 more
doaj   +1 more source

Affordability of in vivo gene therapy. Problems and potential solutions

Фармакоэкономика, 2020
Aim. To review foreign approaches to the evaluation and financing of in vivo gene therapy drugs.Materials and Methods. The first stage of the review included the systematic search for publications of clinical-economic studies (CES) on in vivo gene ...
V. V. Omelyanovskiy, N. Z. Musina, V. A. Lemeshko, A. A. Antonov, F. V. Gorkavenko   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

CONTROL MONITORING IN THE SYSTEM OF STATE FINANCIAL CONTROL METHODS [PDF]

Legal Bulletin
Federal Law No. 432-FZ of November 28, 2025, amended the Budget Code of the Russian Federation, supplementing the methods of implementing state financial control stipulated by Article 267.1 with a method known as control monitoring, carried out by the ...
MIRONOVA S.M.
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The use of the level of evidence and grade of recommendations scales in developing clinical guidelines in the Russian Federation

Фармакоэкономика, 2019
Aim – analyze the existing systems for assessing the levels of evidence (LE-scales) and grades of recommendation (GR-scales) in the development of clinical guidelines in the Russian Federation. Materials and Methods.
N. I. Zhuravleva, L. C. Shubina, O. A. Sukhorukikh   +2 more
doaj   +1 more source