Results 71 to 80 of about 4,189,816 (303)
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
, 2009 The anomalous chemical abundances and the structure of the Edgewood-Kuiper belt observed in the solar system constrain the initial mass and radius of the star cluster in which the sun was born to $M\simeq500$ to 3000 \msun and $R\simeq 1$ to 3 pc.
Zwart, S. Portegies
core +2 more sources
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
The Helios mechanical despin drive assembly for the high-gain antenna reflector [PDF]
, 1976 Helios is the German-American solar probe which comes within 0.31 Astronomical Units of the sun. A special thermal design and a dry lubrication system have resulted in successful operation up to now, with Helios having finished its first orbit around the
Mueller, E. J. W.
core +1 more source
, 2011 More than 635 000 positional observations (mostly radiotechnical) of planets and spacecraft (1961-2010), have been used for estimating possible changes of the gravitation constant, the solar mass, and semi-major axes of planets, as well as the value of ...
A.J. Hundhausen +31 more
core +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Some ideas about the formation of the Earth
Мінеральні ресурси України, 2017 From the side of teachers of the general geology and the minerals in the College of Geologic Technologies of Taras Shevchenko National University of Kyiv the existing hypothesis about forming the Universe, the Solar System, the Earth and the Earth’s ...
V. O. Shyrin, M. K. Gurska
doaj
, 2018 The possibility that the chemical composition of the solar atmosphere has been affected by radiative dust cleansing of late and weak accretion flows by the proto-sun itself, is explored.
Gustafsson, Bengt
core +1 more source
Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer +11 more
wiley +1 more source