A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
Body Size-Related Thermal Acclimation and Underlying Gene Expression Mechanisms in Workers of the Red Fire Ant <i>Solenopsis invicta</i>. [PDF]
Xu J +5 more
europepmc +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Multienzyme cascade biotransformation of L-Tyrosine to Danshensu by engineered Escherichia coli. [PDF]
Xiong T +7 more
europepmc +1 more source
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Synthesis, Structural and Luminescence Properties of Mn<sup>4+</sup>-Activated Medium-Entropy Perovskites (La<sub>1/3</sub>Gd<sub>1/3</sub>Y<sub>1/3</sub>)<sub>1-<i>x</i></sub><i>M<sub>x</sub></i>AlO<sub>3-<i>δ</i></sub> (<i>M</i> = Ca, Sr). [PDF]
Padole AS +6 more
europepmc +1 more source
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Fluid-layer-assisted mold temperature control for injection-molded bridge-type compliant mechanisms: Experimental thermal validation and simulation-based benchmarking against conventional cooling channels. [PDF]
Minh PS, Do TT, Chuong PN, Dang HS.
europepmc +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source

