Results 71 to 80 of about 1,547,004 (264)

Heavy Scalar, Vector, and Axial-Vector Mesons in Hot and Dense Nuclear Medium

Advances in High Energy Physics, 2014
In this work we shall investigate the mass modifications of scalar mesons (D0; B0), vector mesons (D*; B*), and axial-vector mesons (D1; B1) at finite density and temperature of the nuclear medium.
Arvind Kumar
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Analysis on the difference of bacterial flora structure and gene function of medium-high-temperature Daqu in Hetao and Yingtan area [PDF]

Zhongguo niangzao
Bacterial flora structure of medium-high-temperature Daqu in the Hetao area of Bayannur, Inner Mongolia was analyzed by high-throughput sequencing technology, the comparative analysis of Alpha and Beta diversity was conducted with the bacterial flora of ...
ZHANG Qing, HOU Qiangchuan, LI Qing, ZHANG Min, REN Guojun, WANG Yao, GUO Zhuang
doaj   +1 more source

Red Blood Cell Stiffness and Adhesion Are Species-Specific Properties Strongly Affected by Temperature and Medium Changes in Single Cell Force Spectroscopy. [PDF]

Molecules, 2021
Baier D, Müller T, Mohr T, Windberger U.   +3 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Does the Temperature of the Distension Medium Affect Pain Perception in Patients undergoing Ambulatory Hysteroscopy? [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Ambulatory Hysteroscopy (AH) has become a valuable tool for modern gynaecologists. However, its success largely depends on the patient’s perception of pain. Advances such as the vaginoscopic technique and the use of smaller instruments have
Sai Kalmegh, Meenal Patvekar
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

In-medium similarity renormalization group at finite temperature

Physical Review C
The study of nuclei at finite temperature is of immense interest for many areas of nuclear astrophysics and nuclear-reaction science. A variety of ab initio methods are now available for computing the properties of nuclei from interactions rooted in Quantum Chromodynamics, but applications have largely been limited to zero temperature.
Isaac G. Smith, Heiko Hergert, Scott K. Bogner   +2 more
openaire   +2 more sources

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source