Results 31 to 40 of about 672,396 (296)

Case report: Successful treatment of human diabetic foot ulcer using low-intensity diagnostic ultrasound combined with microbubbles: Two cases

Frontiers in Endocrinology, 2022
BackgroundDiabetic foot ulcer (DFU) is one of the serious complications of diabetes, which has high disability rate and mortality. Low-intensity ultrasound combined with microbubbles in blood circulation can enhance the blood perfusion effect of local ...
Xiaojuan Zhang, Ying Cheng, Ling Pei, Jie Tao, Rui Wang, Zhong Chen   +5 more
doaj   +1 more source

NLRP3 inflammasome in peripheral blood monocytes as a risk factor for early -onset preeclampsia

BMC Pregnancy and Childbirth, 2023
Introduction As a leading cause of pregnancy and fetal mortality, pre-eclampsia impacts about 5–8% of pregnancies globally. To date, few studies have focused on the role played by (NOD)-like receptors protein 3 (NLRP3) in peripheral blood in early-onset ...
Hong Yang, Mo Ai, Yanqiu Guo, Bingfen Li, Cong Liu, Dongying Qu   +5 more
doaj   +1 more source

A Bioresorbable Neural Interface for On‐Demand Thermal Pain Block

Advanced Functional Materials, EarlyView.
Bioresorbable, implantable neural electronics provide dynamic, on‐demand thermal modulation of peripheral nerves for safe, drug‐free pain relief. A microscale thin‐film heater and temperature sensor embedded within biodegradable encapsulants enable precise temperature control via real‐time feedback.
Jeonghwan Park, Hak‐Young Ahn, Minho Seong, Taehoon Kim, Yulin Zhou, Yameng Xu, Jaehee Lee, Ritika Raj Menghani, Yujin Choi, Minsu Park, Nadir Muzaffar, Youngeun Lee, Seung Gi Seo, Jong Uk Kim, Sang Min Won, Jahyun Koo, Elena Aprea, Taeyeon Kim, Ying Yan, Matthew R. MacEwan, Wilson Z. Ray, Raudel Avila, Geumbee Lee, John A. Rogers   +23 more
wiley   +1 more source

Antimicrobial Efficacy of a Taurolidine‐Based Antimicrobial Compound on Contaminated Surfaces Simulated in a Standardized 4‐Field Test

Advanced Healthcare Materials, EarlyView.
As implantable medical devices become indispensable to modern medicine, a silent threat grows alongside them: device‐associated infections. Despite decades of antibiotic innovation, infection rates keep climbing, costing lives and billions in healthcare expenses.
Benito Baldauf, Hendrik Bonnemeier, Ernest W. Lau, Jana Hummel, Reinhard Vonthein, Ojan Assadian   +5 more
wiley   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

A Biomimetic Norepinephrine‐Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical‐Sized Bone Defects

Advanced Science, EarlyView.
Inspired by the composition and structure of native bone tissue and its complex interplay of biological signals, a norepinephrine‐loaded biomimetic mineralized electrocompacted collagen scaffold (NE‐MEC) is developed capable of simultaneously supporting osteogenesis, neural repair, angiogenesis, and immune modulation.
Zhengyun Ren, Zhaojun Wu, Anhang Wu, Hui Zhang, Jiachen Lu, Jiahao Zhang, Jie Weng, Jinhua Zhang, Song Chen, Huan Tan, Tailin Guo   +10 more
wiley   +1 more source

Swedish farmers' approval of nudges

Agribusiness, EarlyView.
Abstract Interest in the use of behavioral policy approaches, such as nudges, has strongly increased over the past years, including in the domains of food, agricultural and environmental policies. While the approval of nudges among the general public has been studied extensively, we know little about the attitude of farmers toward nudging. Farmers may (
Liesbeth Colen, Leon Englberger, Jens Rommel   +2 more
wiley   +1 more source

Enhancing Surgical Efficiency and Cost‐Effectiveness With TaTME‐Combined Robot‐Assisted Surgery for Lower Rectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Robot‐assisted rectal surgery (RAS) offers improved dexterity and visualization; however, the high cost of equipment and consumables remains a major challenge for hospital management. At our institution, we have adopted a combined approach using transanal total mesorectal excision (TaTME) for lower rectal cancers, aiming to shorten ...
Takeru Matsuda, Hiroshi Hasegawa, Yasunori Otowa, Masayuki Ando, Tomoaki Aoki, Yasufumi Koterazawa, Naoki Urakawa, Hironobu Goto, Shingo Kanaji, Yoshihiro Kakeji   +9 more
wiley   +1 more source

The Insistence of Blackness and the Persistence of Antiblackness in Ireland

Australian Journal of Social Issues, EarlyView.
ABSTRACT This paper positions Ireland as a critical site for examining the insistence of blackness and an antiblackness created and sustained through Irish ethnonationalist imaginaries and exclusionary processes. Drawing on connected sociologies and Irish Black Studies, this enquiry argues that antiblackness in Ireland operates as a generational force,
Philomena Mullen
wiley   +1 more source

On the Prospects for African Philosophy in Australia

Australian Journal of Social Issues, EarlyView.
ABSTRACT This paper grapples with the situation of people of African descent in Australia by working through the constitution of the body of academic philosophy in the country. It contends with the parochialism of the Australian philosophical community and the prospects for the cultivation of greater pluralism. Taking African philosophy as one possible
Bryan Mukandi
wiley   +1 more source