Results 61 to 70 of about 44,131 (296)

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

A rare case of acute poster ior reversible encephalopathy syndrome involving brainstem in a child

open access: yesJournal of Acute Disease, 2016
Posterior reversible encephalopathy syndrome (PRES) is a rare entity involving brainstem in very rare reported cases. We describe here the case of a boy who presented to the emergency department for headaches and strabismus.
Olfa Chakroun-Walha   +4 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Characteristics of the British and the Irish people in movies during the Troubles

open access: yes, 2019
Práce pojednává o problematice severoirského konfliktu, známého také jako The Troubles, z pohledu filmového průmyslu a filmů spojených s tímto tématem.
Bendásek, Tomáš
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

The Verigin Volkonsky Brothers and the Practice of Polynomy during the Time of Troubles

open access: yesВопросы ономастики
This article examines the cultural phenomenon of bearing multiple Christian names (polynomy) through the case of the Verigin branch of the Volkonsky family, participants in the events of the Time of Troubles (1598–1613).
Sergey Yurievich Shokarev
doaj   +1 more source

On the Function of the Tula Basqaqs in the Northeastern Part of the Chernigov Principality in the thirteenth and fourteenth centuries

open access: yesЗолотоордынское обозрение, 2020
Research objectives: Identification of the set of reasons that led to the emergence, function, and disappearance of the Golden Horde’s administrative structures not related to the ruling princely dynasty in the northeastern territories of the Chernigov ...
Mayorov A.A.
doaj   +1 more source

Crisis of Confidence: Anglo-Irish Relations in the Early Troubles

open access: yes, 2010
This ground-breaking new book studies the diplomatic and security history of relations between Ireland and Britain, giving context to the role of Anglo-Irish relations in the early years of the Northern Ireland Troubles.
CRAIG, Tony
core  

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

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