Results 21 to 30 of about 138,568 (265)

Gut–ovary axis and multiomic insights into PCOS in a DHEA-induced rat model

open access: yesScientific Reports
This study aims to investigate gut microbiota and metabolomes of fecal, cecum, serum, and ovarian tissues in a DHEA-induced rat polycystic ovary syndrome (PCOS) model and explore the gut–ovary axis in PCOS pathogenesis.
Zhi Chen   +11 more
doaj   +1 more source

The Post-Secular Turn: Enlightenment, Tradition, Revolution

open access: yesEidos. A Journal for Philosophy of Culture, 2019
The aim of this essay is to give a general and accessible overview of the so called “post-secular” turn in the contemporary humanities. The main idea behind it is that it constitutes an answer to the crisis of the secular grand narratives of modernity ...
Agata Bielik-Robson
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Clinical Efficacy of Hexue Tongbi Formula on Oxaliplatin-Induced Peripheral Neuropathy: A Randomized Controlled Study

open access: yesIntegrative Cancer Therapies
Aim: The aim of this study was to analyse the effiacy of HeXue Tongbi Formula in the treatment of oxaliplatin-induced perpheral neuropathy. Method: An open randomized, non-blind, controlled study was conducted at the First Affiliated Hospital of ...
Lingling Sun MD   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Bolognese Tradition: Ancient Tradition or Modern Myth?

open access: yesActa Periodica Duellatorum, 2023
This article discusses the modern interpretation that Bologna produced a distinctive regional martial tradition, based on the existence of similar treatises.
Rob Runacres
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Perspektif Mahasiswa Muslim FKIP Universitas Mataram terhadap Ajaran Islam dalam Tradisi “Nyongkolan” sebagai Bagian dari Prosesi Pernikahan Masyarakat Adat Sasak Lombok

open access: yesManazhim, 2023
Nyongkolan is one of the processions in a series of wedding traditions of the Sasak tribe of Lombok, West Nusa Tenggara. As a culture that is preserved in the midst of a majority Muslim community, the tradition of Nyongkolan which is carried out with ...
Lenny Herlina
doaj   +1 more source

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