Results 201 to 210 of about 1,170,323 (284)

A comparison of dose between cone beam computed tomography and conventional computed tomography in broad beam geometry. [PDF]

Radiat Prot Dosimetry
Larsson J, Grönqvist Z, Carlstein O, Asplund S.   +3 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Biomimetic Dual-Strategy Adaptive Differential Evolution for Joint Kinematic-Residual Calibration with a Neuro-Physical Hybrid Jacobian. [PDF]

Biomimetics (Basel)
Ma X, Zhao Y, Li Z.
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Effect of storytelling on learning about the institutionalization of Unified Health System: randomized controlled trial. [PDF]

Rev Bras Enferm
Silva ÁDME, Valle ARMDC, Borges JWP, Moreira TMM, Bezerra MAR, Santos DCMD.   +5 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Leveraging Spot-Gene Heterogeneous Graphs for Unified Spatially Resolved Transcriptomics Domain Detection on Single-Slice and Multi-Slice Data. [PDF]

Genes (Basel)
Xia L, Ding Z, Zhang X, Qian K, Li H.
europepmc   +1 more source

Unified Zonal Method Based on the Fortified Solution Algorithm

Unified Zonal Method Based on the Fortified Solution Algorithm
Computational Fluid Dynamics, with the aid of supercomputers, are becoming in the matured stage for both physical research problems and practical engineering problems. Currently, a method handling complex body configurations and increasing accuracy of the simulations are important topics in the CFD research.
openaire  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Complex soliton wave patterns of Gross-Pitaevskii systems: application in quantum and optical engineering. [PDF]

Sci Rep
Bilal M, Alawaideh YM, Rehman SU, Popa IL, Al-Khamiseh BM, Ghannam H.   +5 more
europepmc   +1 more source