Results 181 to 190 of about 129,098,539 (245)

Single‐Cell Profiling Reveals Clonally Expanded CX3CR1+ T Cells in Anti‐NMDA Receptor Encephalitis

Advanced Science, EarlyView.
CX3CR1+ T cells are associated with peripheral and central immune alterations in anti‐NMDA receptor encephalitis (NMDAR‐E). They show potential responsiveness to GluN1 (NR1) peptides, potential interactions with peripheral B cells, clonal expansion, increased CD137/CD154 expression, and inflammatory cytokine production. Their preferential cerebrospinal
Lin Yan, Erdi Zhang, Yuwen Ma, Zirui Meng, Sisi Li, Yimeng Ren, Xiaohe Tian, Yangyi He, Giuseppe Battaglia, Dong Zhou, Yun Liao, Binwu Ying, Jinmei Li, Minjin Wang   +13 more
wiley   +1 more source

Geographic Disparities in Access to Broadband, Ambulance Services, and Health Care and Implications for Telehealth.

JAMA Health Forum
Jewell C, O'Connor H, Griffin TE, Mah SM, Holston BL, Troiano E, Jonk YC.   +6 more
europepmc   +1 more source

Mapping mosquitoes and their associated pathogens in West Africa. [PDF]

Infect Dis Poverty
Xu Q, Wang CY, Liu J, Ye RZ, Wang XY, Wang BY, Wang SS, Zhao L, Cao WC.   +8 more
europepmc   +1 more source

Mapping Embryonic Mouse Lung Development Using Enhanced Spatial Transcriptomics

Advanced Science, EarlyView.
The mammalian lung contains ∼50 cell types arranged along the airway epithelium. Here, deterministic barcoding sequencing (DBiT‐seq) is optimized to nearly double transcript recovery, enabling highly sensitive spatial mapping of the embryonic mouse lung.
Pengfei Zhang, Benjamin K. Law, Niles Huang, Katharine Goodwin, Celeste M. Nelson, Michelle M. Chan   +5 more
wiley   +1 more source

Electron‐Beam Enables Spatially Resolved Defect‐Mediated Work Function Modulation in FAPbI3 Perovskite Thin Films

Advanced Science, EarlyView.
Electron‐beam irradiation enables defect‐mediated work function modulation in metal halide perovskites by regulating interstitial iodides. This approach allows continuous Fermi‐level tuning and spatially resolved formation of lateral surface‐potential‐defined junctions with built‐in potential.
Hyeonho Park, Seung‐Gu Choi, Jae‐Hwan Kim, Dong‐Jun Lee, Sung‐Kwang Jung, Gwanghee Lee, HongSeok Kim, Kyung‐Hwan Jin, Jin‐Wook Lee, Seong Heon Kim   +9 more
wiley   +1 more source

Fatal Cutaneous Mucormycosis Initially Misdiagnosed as Necrotizing Fasciitis in an Uncontrolled Diabetic Patient: A Case Report Highlighting Diagnostic Delay. [PDF]

Int Med Case Rep J
Hartantri Y, Gunadi SV, Ferdian F, Wijaya I, Hidayah RMN, Aisyah NN, Nugraha NF, Fauziah N.   +7 more
europepmc   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

Advanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang   +11 more
wiley   +1 more source

Matrix Rigidity Mechanoprimes Microglia for Inflammation Through Cytoskeletal‐to‐Nuclear Signaling and 3D Spatio‐Epigenomic Remodeling

Advanced Science, EarlyView.
Pathological tissue rigidity mechanoprimes microglia by enhancing actin cytoskeleton–nucleus coupling and chromatin opening at rigidity‐responsive cis‐regulatory elements (mechanoCREs). Subsequent NF‐κB/p65 signaling converges on this permissive regulatory state to amplify inflammatory gene expression and microglial activation.
Yu Xuan Meng, Jaegeon Joo, Yu Meng Li, Cheng Ji Li, Ali Taghizadeh, Seung Jae Shin, Buuvee Bayarkhangai, Tae‐Woo Ha, Sak Lee, Jaewoo Chung, Bo‐Eun Yoon, Hye Sung Kim, Inkyung Jung, Jung‐Hwan Lee, Kam W. Leong, Hae‐Won Kim   +15 more
wiley   +1 more source