Results 61 to 70 of about 3,194,118 (301)
Year in Review 2018 by the Brazilian Gastrointestinal Tumors Group: Neuroendocrine Tumors
Brazilian Journal of Oncology, 2018 Neuroendocrine tumors (NET) constitute a heterogeneous group of neoplasms with variable prognoses and clinical presentations. Therefore their therapeutic management is challenging, involving a real multidisciplinary approach composed of medical ...
Duilio R. Rocha +2 more
doaj +1 more source
Genetic influences in different aspects of language development: The etiology of language skills in 4.5 year-old twins [PDF]
, 2005 The genetic and environmental etiologies of diverse aspects of language ability and disability, including articulation, phonology, grammar, vocabulary, and verbal memory, were investigated in a U.K.
Oliver, B. +32 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Regulatory Year in Review: 2016
, 2016 With the regulatory stories of 2016 coming to a close, The Regulatory Review would like to reflect on the many important regulatory developments in the United States and around the world during 2016.
The Regulatory Review
core +1 more source
Scotland's Towns Partnership: A (Covid) Year in Review [PDF]
, 2021 First paragraph: Towards the end of each May, thoughts at Scotland’s Towns Partnership (STP) often turn reflective. As we head towards our Annual Towns Tea Party and our AGM (2nd June), we look back on the year.
Sparks, Leigh
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
The year in review: progress in brain barriers and brain fluid research in 2018
Fluids and Barriers of the CNS, 2019 This editorial focuses on the progress made in brain barrier and brain fluid research in 2018. It highlights some recent advances in knowledge and techniques, as well as prevalent themes and controversies.
Richard F. Keep +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source