Results 141 to 150 of about 1,504,626 (344)
Advanced Science, EarlyView.This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin +12 more
wiley +1 more source
COVID-19: Thematic Guidance: Securing Academic Standards and Supporting Student Achievement [PDF]
, 2020 core
Advanced Science, EarlyView.This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård +19 more
wiley +1 more source
Thematic Annotation: extracting concepts out of documents [PDF]
, 2004 Contrarily to standard approaches to topic annotation, the technique used in this work does not centrally rely on some sort of -- possibly statistical -- keyword extraction. In fact, the proposed annotation algorithm uses a large scale semantic database -
Andrews, Pierre, Rajman, Martin
core +1 more source
Advanced Science, EarlyView.This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen +7 more
wiley +1 more source
Advanced Science, EarlyView.The design employs heterogeneous wettability surfaces that construct stable oil‐water interfaces to achieve robust and rapid reversible adhesion. Linear enhancement of adhesion strength is realized through multi‐interface patterning. This adhesive enables rapid on‐demand detachment within five seconds via voltage‐induced electrolysis, offering a level ...
Xiaokai Li +11 more
wiley +1 more source
Thematic clubs and the supremacy of network externalities [PDF]
We raise the problem of the minorities survival in the presence of positive network externalities. We rely on the example of thematic clubs to illustrate why and in which circumstances such survival problems might appear, first considering the case of ...
GABSZEWICZ, Jean J., RESENDE, Joana
core
Aiming to be a breastfeeding mother in a neonatal intensive care unit and at home: a thematic analysis of peer‐support group discussion in social media [PDF]
, 2014 Hannakaisa Niela‐Vilén +3 more
openalex +1 more source
Peptide‐Incorporated Biomaterials Promote Regeneration of Peripheral Nerve Injuries
Advanced Science, EarlyView.Peptide‐incorporated biomaterials provide precise, tunable biological cues that mimic functional protein domains to regulate behaviors of neurons, Schwann cells, immune cells, and endothelial cells, thereby enhancing axon elongation, Schwann cell support, inflammatory microenvironment modulation, and vascularization, offering a promising alternative to
Zhiwei Zhao +5 more
wiley +1 more source