Results 141 to 150 of about 1,614,627 (311)

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

Participants MAPS 10

, 2017
La liste des participants prévus pour MAPS 10 est disponible Parmi plus de 50 demandes, les heureux candidats sélectionnés sont: Ansobi Onsimbie Papy Université de Kinshasa Kinshasa Barge Olivier CNRS Berrias-et-Casteljau Baudrit Cedric INRA ...
Réseau MAPS
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Multi‐Technique Integration Identifies O‐GlcNAc Transferase in Fibroblast‐Like Synoviocytes as a Therapeutic Target for Rheumatoid Arthritis

Advanced Science, EarlyView.
AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie, Jie Huang, Chunhao Cao, Zhenchao Tang, Xingchen Li, Jianmin Guo, Xinxin Chen, Fang Wang, Dongyi He, Jie Li, Yu Du, Bing He, Jianhua Yao, Aiping Lu, Chao Liang   +14 more
wiley   +1 more source

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

A Preclinical Multifunctional Capsule Robot with Unified Diagnosis and Targeted Thermal Therapy for Gastrointestinal Diseases

Advanced Science, EarlyView.
A proof‐of‐concept multifunctional capsule robot integrates diagnostic imaging, magnetic navigation, wireless power transfer, and targeted thermotherapy for gastrointestinal applications. Magnetically guided positioning and stable wireless power enable localized thermal ablation, achieving controlled heating and high cell mortality in vitro.
Heng Zhang, Yichong Sun, Xiaoting Zhang, Chi‐Kwan Lee, Zheng Li, Yehui Li, Huarong Chen, Paul D. Mitcheson   +7 more
wiley   +1 more source

Modalités de participation MAPS 13

, 2020
Modalités de participation La participation à MAPS 13 est soumise à sélection : les dossiers de candidature seront étudiés par le comité scientifique. Les tarifs sont fixés en fonction des statuts (voir ci-dessous).
Réseau MAPS
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Adaptive Conductive Systems: Enabling Deformable Electronics Through Engineered Materials, Circuits, and Intelligent Systems

Advanced Science, EarlyView.
This review presents the research advances of adaptive conductive systems from the perspective of materials, circuits, systems, and applications. Deformable conductors consist of substrates/matrices and conductive materials, structural design of circuit interconnections, fabrication of circuit interconnections, as well as intelligent systems ...
Yufei Lu, Siyu Liang, Jingyi Niu, Jie Chen, Shuo Zhang, Hongjian Zhang, Dongsheng Jia, Wei Huang   +7 more
wiley   +1 more source

Publication liée à MAPS

, 2014
Mapsiennes, Mapsiens, Depuis Mars 2014 un vaste chantier de mise en commun et d'édition de toutes les fiches et modèles ayant été produit dans le cadre de MAPS est en cours.
Réseau MAPS
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Dates à retenir MAPS 13

, 2020
A vos agendas ! Voici les dates à retenir pour MAPS 13 Lancement  de l'appel à candidature : 22 janvier 2020 Date limite de dépôt des candidatures : 22 février 2020 repoussée au 15 mars via le formulaire en ligne, voir sur cette page Notification d ...
Réseau MAPS
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Geographical information system (GIS) in decision support to control malaria – a case study of Koraput district in Orissa, India malaria – a case study of Koraput district in Orissa, India [PDF]

Journal of Vector Borne Diseases, 2009
Annjaan Daash, Aruna Srivastava, B.N. Nagpal, Rekha Saxena, Sanjeev Kumar Gupta   +4 more
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