Results 21 to 30 of about 34,208 (235)

Neural information processing in cognition: we start to understand the orchestra, but where is the conductor?

Frontiers in Computational Neuroscience, 2016
Research in neural information processing has been successful in the past, providing useful approaches both to practical problems in computer science and to computational models in neuroscience.
Guenther ePalm
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Pycabnn: Efficient and Extensible Software to Construct an Anatomical Basis for a Physiologically Realistic Neural Network Model

Frontiers in Neuroinformatics, 2020
Physiologically detailed models of neural networks are an important tool for studying how biophysical mechanisms impact neural information processing. An important, fundamental step in constructing such a model is determining where neurons are placed and
Ines Wichert, Ines Wichert, Sanghun Jee, Sanghun Jee, Erik De Schutter, Erik De Schutter, Sungho Hong   +6 more
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Unit testing, model validation, and biological simulation [version 1; referees: 2 approved, 1 approved with reservations]

F1000Research, 2016
The growth of the software industry has gone hand in hand with the development of tools and cultural practices for ensuring the reliability of complex pieces of software. These tools and practices are now acknowledged to be essential to the management of
Gopal P. Sarma, Travis W. Jacobs, Mark D. Watts, S. Vahid Ghayoomie, Stephen D. Larson, Richard C. Gerkin   +5 more
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From phenomenological to biophysical models of seizures

Neurobiology of Disease, 2023
Epilepsy is a complex disease that requires various approaches for its study. This short review discusses the contribution of theoretical and computational models.
Damien Depannemaecker, Aitakin Ezzati, Huifang E. Wang, Viktor Jirsa, Christophe Bernard   +4 more
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Detecting Multiple Change Points Using Adaptive Regression Splines With Application to Neural Recordings

Frontiers in Neuroinformatics, 2018
Time series, as frequently the case in neuroscience, are rarely stationary, but often exhibit abrupt changes due to attractor transitions or bifurcations in the dynamical systems producing them.
Hazem Toutounji, Daniel Durstewitz, Daniel Durstewitz   +2 more
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Cell-intrinsic mechanisms of temperature compensation in a grasshopper sensory receptor neuron

eLife, 2014
Changes in temperature affect biochemical reaction rates and, consequently, neural processing. The nervous systems of poikilothermic animals must have evolved mechanisms enabling them to retain their functionality under varying temperatures.
Frederic A Roemschied, Monika JB Eberhard, Jan-Hendrik Schleimer, Bernhard Ronacher, Susanne Schreiber   +4 more
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Learning prediction error neurons in a canonical interneuron circuit

eLife, 2020
Sensory systems constantly compare external sensory information with internally generated predictions. While neural hallmarks of prediction errors have been found throughout the brain, the circuit-level mechanisms that underlie their computation are ...
Loreen Hertäg, Henning Sprekeler
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Absence of the Fragile X messenger ribonucleoprotein alters response patterns to sounds in the auditory midbrain

Frontiers in Neuroscience, 2022
Among the different autism spectrum disorders, Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability. Sensory and especially auditory hypersensitivity is a key symptom in patients, which is well mimicked in the Fmr1 ...
Jérémie Sibille, Jérémie Sibille, Jérémie Sibille, Jérémie Sibille, Jérémie Sibille, Jens Kremkow, Jens Kremkow, Jens Kremkow, Jens Kremkow, Ursula Koch, Ursula Koch, Ursula Koch   +11 more
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Clusters of cooperative ion channels enable a membrane-potential-based mechanism for short-term memory

eLife, 2020
Across biological systems, cooperativity between proteins enables fast actions, supra-linear responses, and long-lasting molecular switches. In the nervous system, however, the function of cooperative interactions between voltage-dependent ionic channels
Paul Pfeiffer, Alexei V Egorov, Franziska Lorenz, Jan-Hendrik Schleimer, Andreas Draguhn, Susanne Schreiber   +5 more
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A dynamic clamp protocol to artificially modify cell capacitance

eLife, 2022
Dynamics of excitable cells and networks depend on the membrane time constant, set by membrane resistance and capacitance. Whereas pharmacological and genetic manipulations of ionic conductances of excitable membranes are routine in electrophysiology ...
Paul Pfeiffer, Federico José Barreda Tomás, Jiameng Wu, Jan-Hendrik Schleimer, Imre Vida, Susanne Schreiber   +5 more
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