Results 91 to 100 of about 1,740,325 (329)
Four lectures on probabilistic methods for data science
, 2016 Methods of high-dimensional probability play a central role in applications for statistics, signal processing theoretical computer science and related fields.
Vershynin, Roman
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FEBS Open Bio, EarlyView.This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley +1 more source
FEBS Open Bio, EarlyView.In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki +3 more
wiley +1 more source
Equivalence of hybrid dynamical systems [PDF]
, 2004 A common theme in theoretical computer science (in particular, the theory of distributed processes and computer-aided verification) and in systems and control theory is to charac-terize systems which are ‘externally equivalent’.
Schaft, Arjan van der
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FEBS Open Bio, EarlyView.We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado +4 more
wiley +1 more source
Proximity Effect Aware Detailed Placement in Electron Beam Lithography
MATEC Web of Conferences, 2018 Proximity effect is one of the most tremendous consequences that produces unacceptable exposures during electron beam lithography (EBL), and thus distorting the layout pattern. In this paper, we propose the first work which considers the proximity effect
Chen Yuhang +4 more
doaj +1 more source
Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
FEBS Open Bio, EarlyView.We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó +7 more
wiley +1 more source
Dynamic construction of pan-genome subgraphs
Open Computer Science, 2020 Marcus et al. (Bioinformatics 2014) proposed to use a compressed de Bruijn graph as a description of a pan-genome, comprising the genomes of many individuals/strains of the same or closely related species. Subsequent work improved the construction of the
Dede Kadir, Ohlebusch Enno
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A theory of consciousness from a theoretical computer science perspective: Insights from the Conscious Turing Machine. [PDF]
Proc Natl Acad Sci U S A, 2022 Blum L, Blum M.
europepmc +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source