Results 61 to 70 of about 4,204,940 (272)

Theoretical models of drivers behavior on the road

open access: yesMedycyna Pracy, 2017
Understanding of mechanisms and factors responsible for the driver behavior on the road is the subject of ongoing interest to transportation psychologists, occupational doctors and engineers.
Marcin Piotr Biernacki
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Review on Research Progress of Pulsating Heat Pipes

open access: yesInventions
Since their invention by Akachi in 1990s, pulsating heat pipes (PHPs) have attracted widespread interest and application in practice, e.g., grinding, chip cooling, the thermal management of batteries, etc., owing to their notable efficiency in heat ...
Shiqiang Fang   +4 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Acceptance of Technology and Academic Writing: Analyze in Perspective of Theoretical Models [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2022
This paper studies the factors that contribute to students' acceptance in improving their technical and academic writing skills by applying digital technology.
Bilquis Ferdousi
doaj  

Theoretical study of hydrogen microstructure in models of hydrogenated amorphous silicon

open access: yes, 2009
We study the distribution of hydrogen and various hydride configurations in realistic models of a-Si:H for two different concentration generated via experimentally constrained molecular relaxation approach (ECMR) [1].
Abragam   +13 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Influence of Reynolds number on theoretical models for trailing vortices [PDF]

open access: yes, 2015
We conduct direct numerical simulations for a NACA0012 airfoil at Reynolds numbers (Re) ranging from 300 to 7000 to determine the wake behavior behind this wing profile. We characterize the structure of the wing-tip vortex, finding a reasonable agreement
Del-Pino-Peñas, Carlos Manuel   +4 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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