Results 61 to 70 of about 1,077,717 (311)

The Language of Popularization: Theoretical and Descriptive Models / Die Sprache der Popularisierung: Theoretische und deskriptive Modelle [PDF]

open access: yes, 2010
Il presente progetto nasce come prosecuzione delle ricerche già sviluppate nell’ambito della ricerca dipartimentale nel biennio 2009/2010; le motivazioni fondamentali che erano alla base di quel progetto appaiono infatti tuttora valide, per due ordini ...
BONGO, Giancarmine
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Theoretical models in nuclearastrophysics [PDF]

open access: yesProceedings of XXXIV edition of the Brazilian Workshop on Nuclear Physics — PoS(XXXIV BWNP), 2012
info:eu-repo/semantics ...
openaire   +3 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

A Modified Tri-Exponential Model for Multi-b-value Diffusion-Weighted Imaging: A Method to Detect the Strictly Diffusion-Limited Compartment in Brain

open access: yesFrontiers in Neuroscience, 2018
Purpose: To present a new modified tri-exponential model for diffusion-weighted imaging (DWI) to detect the strictly diffusion-limited compartment, and to compare it with the conventional bi- and tri-exponential models.Methods: Multi-b-value diffusion ...
Qiang Zeng   +5 more
doaj   +1 more source

Compositionality and Model-Theoretic Interpretation

open access: yesJournal of Logic, Language and Information, 2001
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +7 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Dissociação e transtornos dissociativos: modelos teóricos Dissociation and dissociative disorders: theoretical models

open access: yesBrazilian Journal of Psychiatry, 1999
A compreensão da experiência dissociativa e das origens dos transtornos dissociativos é difícil devido à complexidade da questão. As contradições da classificação são decorrentes das dificuldades de se construir uma teoria da mente abrangente que ...
Paulo Jacomo Negro Junior   +2 more
doaj   +1 more source

Explaining usage of process modeling grammars : comparing three theoretical models in the study of two grammars [PDF]

open access: yes, 2010
Our objective was to determine the factors that lead users to continue working with process modeling grammars after their initial adoption. We examined the explanatory power of three theoretical models of IT usage by applying them to two popular process ...
Recker, Jan C., Jan Recker
core   +1 more source

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