Results 41 to 50 of about 1,735,409 (325)

Local ligand concentration gradients induced by the plasma membrane

open access: yesiScience
Summary: The plasma membrane is a dynamic structure surrounded by the extracellular matrix. Although stimulation of transmembrane proteins by soluble ligands takes place in this environment, its influence on receptor activation is usually overlooked.
Ágnes Szabó   +6 more
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Quantum corrections to finite radius holography and holographic entanglement entropy

open access: yesJournal of High Energy Physics, 2020
We calculate quantum corrections to holographic entanglement entropy in the proposed duality between T T ¯ $$ T\overline{T} $$ -deformed holographic 2D CFTs and gravity in AdS3 with a finite cutoff.
William Donnelly   +4 more
doaj   +1 more source

Gravitational and electromagnetic radiation from binary black holes with electric and magnetic charges: elliptical orbits on a cone

open access: yesEuropean Physical Journal C: Particles and Fields, 2021
Extending the electromagnetic and gravitational radiations from binary black holes with electric and magnetic charges in circular orbits in Liu et al. (Phys. Rev.
Lang Liu   +5 more
doaj   +1 more source

Optical Conductivity in the Copper Oxide Materials

open access: yes, 1998
The frequency- and temperature-dependent optical conductivity of the copper oxide materials in the underdoped and optimal doped regimes are studied within the t-J model.
Shiping Feng   +2 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Mochima theoretical physics spring school [PDF]

open access: yesCondensed Matter Physics, 2006
The Mochima theoretical physics spring school on the Foundations of statistical and mesoscopic physics took place in Mochima, Edo. Sucre, Venezuela, between the 20th and 24th of June 2005.
B.Berche, A.Donoso, R.Paredes
doaj  

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

open access: yesFEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh   +7 more
wiley   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

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