Results 21 to 30 of about 5,256 (260)

The formulation of mucoadhesive drug form for topical application in the oral cavity - application, manufacturing technology and testing methods [PDF]

Farmacja Polska, 2021
There are over four hundred different diseases occurring within the oral cavity. These include, among others, mucositis, periodontitis, gingivitis, caries, oral infections, which are usually treated topically. Active substances for topical application in
Michał Krzysztof Kołodziejczyk, Monika Klimczuk, Justyna Kołodziejska, Małgorzata Godlewska, Michał Nachajski   +4 more
doaj   +1 more source

Mean Stress Effect on the Axial Fatigue Strength of DIN 34CrNiMo6 Quenched and Tempered Steel

Metals, 2018
The present study consists of a theoretical and experimental investigation of the effect of axial mean stresses on the high cycle fatigue behaviour of DIN 34CrNiMo6 high strength steel in quenched and tempered conditions.
Luis Pallarés-Santasmartas, Joseba Albizuri, Alexander Avilés, Rafael Avilés   +3 more
doaj   +1 more source

Local zigzag effects and brittle delamination fracture of n-layered beams using a structural theory with three displacement variables

Fracture and Structural Integrity, 2020
Equivalent single layer theories for layered beams effectively and accurately predict global displacements and internal force and moment resultants using a limited number of displacement variables.
Roberta Massabò, Ilaria Monetto
doaj   +1 more source

Analytical and Experimental Investigation into Pre-Stressed Carbon Fiber Reinforced Polymer (CFRP) Fatigue Retrofits for Steel Waterway Lock-Gate Structures

Metals, 2022
Lock gates are an important part of the transportation infrastructure within the United States (US). Unfortunately, many existing lock gates have reached or exceeded their initial design lives and require frequent repairs to remain in service ...
Christine Lozano, Maggie Langston, Mohammad H. Kashefizadeh, Gary S. Prinz   +3 more
doaj   +1 more source

Damage Characteristics of Surrounding Rock Subjected to VCR Mining Blasting Shock

Shock and Vibration, 2015
For limiting the damage range caused by explosive shock loads in vertical crater retreat (VCR) mining, the blasting damage characteristics of surrounding rock were studied by two methods: numerical simulation and ultrasonic testing.
Nan Jiang, Chuanbo Zhou, Xuedong Luo, Shiwei Lu   +3 more
doaj   +1 more source

On structural computations until fracture based on an anisotropic and unilateral damage theory [PDF]

International Journal of Damage Mechanics, 2013
This paper describes the formulation and numerical implementation of a family of anisotropic and unilateral damage models for the prediction of damage and final rupture in engineering structures. The damage can be load oriented, microstructure oriented, or (for the first time within this modeling framework) softening.
Genet, Martin, Marcin, Lionel, Ladevèze, Pierre   +2 more
openaire   +1 more source

Grain kernel damage during threshing: a comprehensive review of theories and models

Journal of Agricultural Engineering
Grain threshing is aimed at separating the grain from the inedible chaff. However, mechanical forces often damage grains, impacting their quality, market value, and germination ability. This comprehensive review examines theories and models developed to
George Ashwehmbom Looh, Fangping Xie, Xiushan Wang, Augustine Ngiejungbwen Looh, Hamdaoui Hind   +4 more
doaj   +1 more source

Concrete damage analysis based on higher-order beam theories using fracture energy regularization

Mechanics of Advanced Materials and Structures, 2022
This paper presents the numerical damage analysis of concrete structures using higher-order beam theories based on Carrera Unified Formulation (CUF). The concrete constitutive relation is modeled using continuum damage mechanics based on a modified Mazars concrete damage model, in which both the tensile and compressive softening behaviors are ...
Shen, J., Arruda, M. R. T, Pagani, A.
openaire   +3 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source