Results 81 to 90 of about 269,986 (219)

M3D-K simulations of beam-driven instabilities in an energetic particle dominant KSTAR discharge

Nuclear Fusion
We perform a systematic simulation study of energetic passing particle-driven instabilities in KSTAR using the kinetic-MHD hybrid code M3D-K. Linear simulation results show that the observed n  = 1 mode in the early phase of the discharge is the low ...
L.L. Zhang, H.G. Jhang, J.S. Kang, Z.M. Sheng, G.Y. Fu   +4 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The energy landscape of magnetic materials

npj Computational Materials
Magnetic materials can display many solutions to the electronic-structure problem, corresponding to different local or global minima of the energy functional.
Louis Ponet, Enrico Di Lucente, Nicola Marzari   +2 more
doaj   +1 more source

Age of Information-Based Optimal Scheduling With Energy Cost Trade-Off for Smart Warehouse: A Deep Reinforcement Learning-Based Approach

IEEE Access
Recent advances in the integration of high-speed mobile networks and real-time IoT devices have facilitated in building of smart warehouses, where a set of beacons and Internet of Things (IoT) devices (or source nodes) can monitor the status of various ...
Sandip Roy, Abhishek Bisht, Ashok Kumar Das, Sachin Shetty   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A comprehensive exploration of structural and electronic properties of molybdenum clusters

APL Materials
Molybdenum clusters, characterized by their unique structure and intriguing catalytic properties, have gained significant attention in recent years. In several existing studies, density functional theory (DFT) methods have been used to find the lowest ...
Yao Wei, Valera Veryazov, Lev Kantorovich   +2 more
doaj   +1 more source

Chromatin Compaction Multiscale Modeling: A Complex Synergy Between Theory, Simulation, and Experiment. [PDF]

Front Mol Biosci, 2020
Bendandi A, Dante S, Zia SR, Diaspro A, Rocchia W.   +4 more
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Magnons from time-dependent density-functional perturbation theory and nonempirical Hubbard functionals

npj Computational Materials
Spin excitations play a fundamental role in understanding magnetic properties of materials, and have significant technological implications for magnonic devices.
Luca Binci, Nicola Marzari, Iurii Timrov
doaj   +1 more source