Results 51 to 60 of about 280,132 (263)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Building Pretorsion Theories from Torsion Theories
Algebras and Representation TheoryAbstract Torsion theories play an important role in abelian categories and they have been widely studied in the last sixty years. In recent years, with the introduction of pretorsion theories, the definition has been extended to general (non-pointed) categories.
Campanini, F., Fedele, F.
openaire +5 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
An Epistemic Analysis of the Concept of Non-Place (Non-Lieu) in Mark Augé
Megaron, 2018 The non-place (non-lieu) concept came to the fore for the first time, with the book 'Non-Lieux, Introduction à une Anthropologie de la Surmodernité', written by Mark Augé in 1992. The book was later translated into many languages.
Rifat Gökhan Koçyiğit
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Social Pedagogical Eyes in the Midst of Diverse Understandings, Conceptualisations and Activities
International Journal of Social Pedagogy, 2012 The concept of social pedagogy consists of two parts. The principal term is ‘pedagogy’ and the qualifying one is ‘social’. The word ‘social’ is used in different ways and contexts.
doaj +2 more sources
Remote Sensing, 2018 Landslides are one of the most common and dangerous threats in the world that generate considerable damage and economic losses. An efficient landslide monitoring tool is the Differential Synthetic Aperture Radar Interferometry (DInSAR) or Persistent ...
Feng Zhao +4 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Theory-building: working the theory-data spectrum
Horizonte, 2019 This article illustrates some implications of the view that data, theory and methods should be treated as a matched set. They are inseparable companions, equally essential parts of processes of scholarly research and dissemination.
Steven Joseph Engler
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source