Results 41 to 50 of about 166,292,975 (307)

Leg dominance influences side-specific directional movement demands during change-of-direction movements in elite youth soccer players

open access: yesFrontiers in Sports and Active Living
IntroductionMonitoring training load in youth soccer is a key component of athlete development. However, limited evidence exists regarding the influence of leg dominance on side-specific directional movement demands during change-of-direction movements ...
Krisztián Havanecz   +9 more
doaj   +1 more source

Game Theory and Evolution [PDF]

open access: yesIEEE Intelligent Systems, 2013
Key concepts are described from the area now known as evolutionary game theory, while also introducing some important applications of these concepts.
Steve Phelps, Michael J. Wooldridge
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

External training load and rating of perceived exertion comparison between different playing styles and winning vs. losing matches in elite tennis

open access: yesFrontiers in Sports and Active Living
IntroductionThis study aims to compare different playing styles on external training load and rating of perceived exertion (RPE) in elite Hungarian junior tennis players during the off-season in winning vs. losing matches.MethodsSixteen elite male junior
Péter János Tóth   +10 more
doaj   +1 more source

COLLECTIVE CRIBBING: MODEL OF PLAYERS' BEHAVIOUR IN TEAM

open access: yesВестник Российского экономического университета имени Г. В. Плеханова, 2017
During one's life a person keeps on facing a dilemma: to attain a set goal by himself or to use team's assistance to make a task easier. A vivid example showing a complexity of choice in similar situation is a process of studying in university, when a ...
Mariya V. Kulabukhova, Olga A. Sokolova
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

A conceptual framework for serious games and its validation

open access: yes, 2010
This research introduces a conceptual framework for the design of serious games and uses the Technology Acceptance Model (TAM) for its validation.
Yusoff, Amri
core   +1 more source

Predicting differential ratings of perceived exertion (dRPE) in youth soccer using decision tree models

open access: yesScientific Reports
This study investigated the relationship between external training load metrics obtained from GPS technology and differentiated ratings of perceived exertion (dRPE) in elite youth soccer players, and evaluated the predictive value of decision tree models
Robert Śliwowski   +5 more
doaj   +1 more source

Economic Harmony—A Rational Theory of Fairness and Cooperation in Strategic Interactions

open access: yesGames, 2022
Experimental studies show that the Nash equilibrium and its refinements are poor predictors of behavior in non-cooperative strategic games. Cooperation models, such as ERC and inequality aversion, yield superior predictions compared to the standard game ...
Ramzi Suleiman
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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