Results 31 to 40 of about 115,024 (305)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Towards a Theory of Age-Group Justice

open access: yes, 1989
Norman Daniels' and Daniel Callahan's recent work attempts to develop and deepen theories of justice in order to accommodate intergenerational moral issues.
Jecker, Nancy S.
core   +1 more source

Beyond Crisis and Ambition: Operative Closure as a Critical Lens for Observing International Environmental Law and the South China Sea

open access: yesGerman Law Journal
Current scholarship often views international environmental law (IEL) through a crisis or ambition lens. The “crisis lens” apologizes for the limitations of doctrinal methods in resolving disputes.
Kenneth Kang
doaj   +1 more source

Comparative Analysis of Modern Criminal Law Principles in Rawls's Theories of Justice and Rousseau's Social Contract [PDF]

open access: yesفلسفه حقوق
The aim of the current study is to conduct a comparative analysis of modern criminal law principles based on John Rawls's theories of justice and Jean-Jacques Rousseau's social contract, as well as to show how these views can lead to the development of a
Afshin Daryabayan, Mohsen Mahmoudi
doaj   +1 more source

Transitional Justice Process and the Justice Theory of Roland Dworkin

open access: yesLaws, 2023
The determination of truth in the aftermath of war aiming at establishing justice and peace is a key element of a transitional justice (TJ) process. The theory of justice of Roland Dworkin deals with an approach in which the interpretation of values such
Helen Gyr
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Investigating the Impact of Jury Sentencing Recommendations Using Procedural Justice Theory [PDF]

open access: yes, 2017
Public confidence in the criminal justice system is critical for the system to function effectively. Two studies investigated the impact of jury sentencing recommendations on public confidence using procedural justice theory.
Antrobus, Emma   +3 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Desert and Distributive Justice in a Theory of Justice

open access: yes, 2002
This paper proceeds as follows. First, I present the standard interpretation of Rawls’s account of desert. I then show how this interpretation is inadequate, bringing to light certain subtleties of the account that give it entirely new meaning.
Moriarty, Jeffrey
core   +1 more source

The Idea of Small Justice [PDF]

open access: yes, 2021
Talk about social or distributive justice, at least among legal and political philosophers, tends to focus heavily on institutions. This way of thinking about justice owes a great deal to John Rawls.
Crowe, Jonathan, Jonathan Crowe
core   +1 more source

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