Results 81 to 90 of about 864,431 (237)

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Energy Conservation in Academic Institutions: An Application of Theory of Planned Behavior

open access: yesRecoletos Multidisciplinary Research Journal, 2019
Energy conservation is a buzzword that cuts across a broad spectrum of stakeholders. It has been widely practiced, developed, and discussed in government, political, and industrial sectors due to its massive impact on tackling issues related to climate ...
Eugenio A. Ermac
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Nurses\u27 Own Birth Experiences Influence Labor Support Attitudes and Behaviors [PDF]

open access: yes, 2016
Objective To describe the attitudes of intrapartum nurses about the importance of and intent to provide professional labor support (PLS); barriers to PLS, such as perceived subjective norms and perceived behavioral control; and relationships among ...
Aschenbrenner, Ann P.   +3 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

The Assessment of the Theory of Planned Behavior Structures on Nutritional Prophylactic Treatment of Anemia in Pregnant Women of Arak City in 2018

open access: yesMajallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2018
Background and Aim: Iron deficiency is one of the most common nutritional problems during pregnancy. The purpose of this study was to assess the theory of planned behavior structures on nutritional prophylactic treatment of anemia in pregnant women of ...
Zahra Jahangiri   +3 more
doaj  

Theory of Planned Behavior’s Method on Knowledge and Preventive Behavior Toward Tuberculosis

open access: yesJurnal Info Kesehatan
Tuberculosis (TB) is an infectious disease that has become a global health concern, with Indonesia being the country with the second-highest number of pulmonary TB cases after India.
Uly Agustine   +6 more
doaj   +1 more source

The Theory of Planned Behavior and Disaster Preparedness.

open access: yesPLoS currents, 2017
Disaster preparedness is defined as actions that ensure resources necessary to carry out an effective response are available before a disaster. Disaster preparedness requires a thorough understanding of the factors that influence performance or nonperformance of disaster preparedness behaviors (DPB).
Najafi, Mehdi   +4 more
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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