Results 31 to 40 of about 30,993 (216)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Identifying the interrelations between subjective walkability factors and walking behaviour: A case study in Jeddah, Saudi Arabia

Transportation Research Interdisciplinary Perspectives
Promoting pedestrian-friendly environments has become a subject of great interest worldwide, as it crosses a wide range of scientific fields. Numerous factors have been proposed to measure the level of walkability, but no consensus has been reached on ...
Abdullh Banger, Anna Grigolon, Mark Brussel, Karin Pfeffer   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Using the Theory of Planned Behaviour when designing motivational letters: Exploring through patient interviews how determinants of behaviour are operationalised in letters of invitation to cardiac rehabilitation

Nursing Practice Today, 2018
Background & Aim: While health behaviour theories are often used to develop written material for health care interventions, descriptions of how to operationalise such theories are lacking in the literature. Paradoxically, it is precisely this information
Corinna Dressler
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Intention to Adopt Islamic Microfinance in the Gambia: The Mediating Role of Attitude

Journal of Islamic Monetary Economics and Finance
This study investigates the factors that influence existing and potential customers’ intention to adopt Islamic microfinance in the Gambia using the Theory of Planned Behavior (TPB).
Cherno Jallow, Mehmet Bulut
doaj   +1 more source

Entrepreneurial intentions: The role of personality traits in perspective of theory of planned behaviour [PDF]

Asia Pacific Journal of Innovation and Entrepreneurship, 2018
Purpose - This study aims to inculcate personality traits in theory of planned behaviour (TPB) and analyze mediation of perceived behavior control (PBC) and attitude toward entrepreneurship. Design/methodology/approach - Data were collected with the help
Muhammad Farrukh, Yazan Alzubi, Imran Ahmad Shahzad, Abdul Waheed, Nagina Kanwal   +4 more
doaj   +1 more source