Results 161 to 170 of about 176,595,669 (299)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Challenges in Theory and Practice Fall 2009

, 2009
Issue of Challenges in Theory and Practice, a publication of the University of Scranton's Panuska College of Professional ...
University of Scranton. Panuska College of Professional Studies
core  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Opening the Black Box of Ayres Sensory Integration^®: Clarifying Mechanisms of Change from Treatment Theory to Participation. [PDF]

Brain Sci
Reynolds S, Andelin L, LaRocca C.
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Challenges in Theory and Practice Fall 2008

, 2008
Issue of Challenges in Theory and Practice, a publication of the University of Scranton's Panuska College of Professional ...
University of Scranton. Panuska College of Professional Studies
core  

"They teach us how to look at the world": student perceptions of traditional behavioral and underrepresented social-structural theoretical content in a graduate public health course. [PDF]

Front Public Health
Harvey M, Castle A, Mehta V.
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Author Correction: Modulation of optical absorption in m-Fe1−xRuxS2 and exploring stability in new m-RuS2

Scientific Reports, 2021
H. Joshi, M. Ram, N. Limbu, D. P. Rai, B. Thapa, K. Labar, A. Laref, R. K. Thapa, A. Shankar   +8 more
doaj   +1 more source

Entrepreneurial Leadership in Business Organizations: A Systematic Review and Meta-Analysis. [PDF]

F1000Res
Amborowati A, Riani AL, Harsono M, Suyono J.   +3 more
europepmc   +1 more source