Results 61 to 70 of about 176,595,669 (299)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Towards an Antipodean theory of space
The paper explores the idea of a critique of Antipodean theory of space as one agenda for the Spatial Theory paradigm in ARCRNSISS. The paper has three parts.
Mitchell, Bill +3 more
core
Obsah ročníku /// Volume Contents
Obsah ročníku / Volume ...
Teorie vědy / Theory of science
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Obsah ročníku /// Volume Contents
Obsah ročníku / Volume ...
Teorie vědy / Theory of science
doaj
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
A Novel Generalized Beamforming Layer Set for Deep Learning Based Acoustic Cavitation Detection
Cavitation is a major issue in hydraulic machinery, causing mechanical damage, efficiency loss and potential system failure. Early detection of cavitation is crucial for predictive maintenance, yet conventional monitoring methods based on pressure and ...
Fangfang Zhu-Zhou +5 more
doaj +1 more source
COARSE-GRAINED MODELING OF PROTEIN STRUCTURE, DYNAMICS AND PROTEIN-PROTEIN INTERACTIONS
Theoretical prediction of protein structures and dynamics is essential for understanding the molecular basis of drug action, metabolic and signaling pathways in living cells, designing new technologies in the life science and material sciences.
ANDRZEJ KOLINSKI +5 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Objectives Recognition of mobile applications within encrypted network traffic holds considerable effects across multiple domains, encompassing network administration, security, and digital marketing.
Marziyeh Bayat +6 more
doaj +1 more source

