Results 151 to 160 of about 59,543 (303)

Carbon Dots for Cancer Theranostics: Synthesis Strategies, Luminescence Properties, and Advances in Bioimaging‐Guided Diagnosis and Therapy

open access: yesChemistry – A European Journal, EarlyView.
Lighting up the path to precision oncology: This review comprehensively summarizes the rational design of carbon dots (CDs), elucidating how core size, surface chemistry, and heteroatom doping dictate their luminescence mechanisms. Special emphasis is placed on engineering NIR‐II emissive CDs for deep‐tissue imaging.
Zekun Yan   +3 more
wiley   +1 more source

PEGylated Phospholipid Micelle-Encapsulated Near-Infrared PbS Quantum Dots for in vitro and in vivo Bioimaging

open access: yesTheranostics, 2012
Surface modification and functionalization of bioconjugated quantum dots (QDs) has drawn great attention for the past few years due to their wide applications in biomedical research.
Rui Hu, Wing-Cheung Law, Guimiao Lin, Ling Ye, Jianwei Liu, Jing Liu, Jessica L. Reynolds, Ken-Tye Yong
doaj  

All‐in‐One Intelligent Hemostatic Sponge: Rapid Hemostasis for Non‐Compressive Wounds With Synergetic Enhanced Antibacterial Efficacy and Self‐Reporting Biodegradation

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Clinicians often concurrently tackle critical challenges including emergency hemorrhage, secondary infection, and the elusive tracking of biodegradation of conventional hemostatic agents for complex wounds. Here, we report an intelligent hemostatic sponge (spCS@AIE) by incorporating aggregation‐induced emission (AIE) nanoparticles with short‐wave ...
Zhicheng Liu   +12 more
wiley   +1 more source

Vascular Endothelial Growth Factor-Delivery Systems for Cardiac Repair: An Overview

open access: yesTheranostics, 2012
Since the discovery of the Vascular Endothelial Growth Factor (VEGF) and its leading role in the angiogenic process, this has been seen as a promising molecule for promoting neovascularization in the infarcted heart. However, even though several clinical
Teresa Simón-Yarza, Fabio R. Formiga, Esther Tamayo, Beatriz Pelacho, Felipe Prosper, María J. Blanco-Prieto
doaj  

A Direct Method to Prepare Zwitterionic Organotrifluoroborates: Ammonium and Sulfonium Derivatives

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Organotrifluoroborates find applications in synthesis, diagnostics, and theranostics. This study outlines a one‐step reaction for producing ammonium and sulfonium trifluoroborate zwitterion derivatives. This method achieves satisfactory yields without the need for expensive reagents.
Vanessa Re   +6 more
wiley   +1 more source

Exploring Theranostic Potentials of Radioiodinated Hypericin in Rodent Necrosis Models

open access: yesTheranostics, 2012
Objectives: The present animal experiments were conducted to evaluate radioiodinated Hypericin (Hyp) for its regional distribution as well as theranostic potentials.Materials and Methods: Rat models of reperfused liver infarction (RLI) and hepatic ...
Junjie Li, Marlein Miranda Cona, Feng Chen, Yuanbo Feng, Lin Zhou, Jie Yu, Johan Nuyts, Peter de Witte, Jian Zhang, Uwe Himmelreich, Alfons Verbruggen, Yicheng Ni
doaj  

Activatable theranostics

open access: yesNanomedicine: Nanotechnology, Biology and Medicine, 2018
openaire   +2 more sources

Photoinduced Solution‐Stable Radicals via Intramolecular Charge Separation From anti‐Kasha Emissive BN‐Azepines

open access: yesElectron, EarlyView.
A series of BN‐azepines with a twisted heptagonal B–N donor–acceptor framework was synthesized, enabling stable photoinduced radicals in solution. Upon photoexcitation, charge separation between the triarylamine donor and boron acceptor yields a longer‐lived triplet state, which can generate a nitrogen radical cation through electron transfer.
Lingjuan Chen   +3 more
wiley   +1 more source

Preparation of Quantum Dot/Drug Nanoparticle Formulations for Traceable Targeted Delivery and Therapy

open access: yesTheranostics, 2012
Quantum dots (QDs) are luminescent nanocrystals with rich surface chemistry and unique optical properties that make them useful as probes or carriers for traceable targeted delivery and therapy applications.
Ken-Tye Yong, Yucheng Wang, Indrajit Roy, Hu Rui, Mark T. Swihart, Wing-Cheung Law, Sang Kyu Kwak, Ling Ye, Jianwei Liu, Supriya D. Mahajan, Jessica L. Reynolds
doaj  

Mechanisms of SCN2A loss of function do not predict presence or phenotype of epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective SCN2A loss‐of‐function (LoF) variants are associated with epilepsy (onset age ≥ 3 months), intellectual disability (ID), and autism spectrum disorder (ASD). Despite numerous identified variants and the description of phenotypic subgroups, relationships between Nav1.2 channel dysfunction and clinical phenotypes remain unclear.
Marsha Tan   +23 more
wiley   +1 more source

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