Results 151 to 160 of about 40,969 (293)

Magnetic Nanoparticles and microNMR for Diagnostic Applications

Theranostics, 2012
Sensitive and quantitative measurements of clinically relevant protein biomarkers, pathogens and cells in biological samples would be invaluable for disease diagnosis, monitoring of malignancy, and for evaluating therapy efficacy.
Huilin Shao, Changwook Min, David Issadore, Monty Liong, Tae-Jong Yoon, Ralph Weissleder, Hakho Lee
doaj  

Localized Prostate Cancer Therapy: Tumor Microenvironment‐Activated Spermine Hydrogel With Real‐Time Autonomous Fluorescence Sensing

Chemistry – A European Journal, EarlyView.
First tumor microenvironment (TME)‐responsive spermine‐loaded hydrogel with autonomous sensing for advanced local therapy of prostate cancer (PCa) is developed. Spermine can be released from the hydrogel to kill the prostate cancer cells specifically under acidic TME.
Ho‐Fai Chau, Wing‐Sze Tam, Gengguo Deng, Yik Hoi Yeung, Christine Yim Ping Wong, Ka Lo Cheng, Zhengxiao Liu, Lijia Yao, Yi Wang, Angelo H. All, Chi‐Fai Ng, Jinming Di, Ka‐Leung Wong   +12 more
wiley   +1 more source

Clinical applications of CD34+ progenitor cell immunophenotyping in myelodysplastic neoplasms—The CytHem SMD French network experience

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Myelodysplastic neoplasms (MDS) are clonal hematopoietic disorders characterized by ineffective hematopoiesis, peripheral cytopenias, and a risk of progression to acute myeloid leukemia. As the disease originates in hematopoietic stem and progenitor cells (HSPCs), flow cytometry (FCM) has emerged as a key approach to interrogate the bone ...
Nicolas Chapuis, Anne‐Catherine Lhoumeau, Stéphanie Mathis, Michel Ticchioni, Valérie Bardet, the French Working Group CytHem‐SMD   +5 more
wiley   +1 more source

All‐in‐One Intelligent Hemostatic Sponge: Rapid Hemostasis for Non‐Compressive Wounds With Synergetic Enhanced Antibacterial Efficacy and Self‐Reporting Biodegradation

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Clinicians often concurrently tackle critical challenges including emergency hemorrhage, secondary infection, and the elusive tracking of biodegradation of conventional hemostatic agents for complex wounds. Here, we report an intelligent hemostatic sponge (spCS@AIE) by incorporating aggregation‐induced emission (AIE) nanoparticles with short‐wave ...
Zhicheng Liu, Yan Zhang, Mengmeng Wang, Ye Li, Heng Sun, Lanqiong Zhang, Xin Bai, Haicheng Wei, Zhi Wang, Hao Guan, Yanzi Xu, Dongfeng Dang, Lingjie Meng   +12 more
wiley   +1 more source

Theranostic Imaging Agents: Integrating Molecular Diagnostics, Precision Therapeutics, and Artificial Intelligence. [PDF]

Biomolecules
Sharma S, Rabbani SA, El-Tanani M, Patni MM, Kumar R, Saini M.   +5 more
europepmc   +1 more source

Influence of 6‐Trifluoromethyluracil Versus Chloride Counterions in the Properties of Bis‐(1,10‐Phenanthroline)chloridecopper(II) Motif: Spectroscopic and In Vitro Biological Activity Assays

European Journal of Inorganic Chemistry, EarlyView.
This work explores the influence of 6‐trifluoromethyluracil versus chloride counterions on the antibacterial and antitumoral activities of bis‐(1,10‐phenanthroline)chloridecopper(II) motif. The counterion modulates antibacterial potency and the identity of the dominant reactive species, while leaving DNA recognition by the shared cation essentially ...
Francisco Mastrobuono‐Cordeiro, Gabriele de M. Pereira, Douglas H. Nakahata, Stefano Scoditti, Fernanda V. P. de V. Azevedo, Letícia P. de Oliveira, Silmara C. L. Frajácomo, Javier Ellena, Pedro H. de O. Santiago, Daniel Reta, Gilberto C. Franchi, Wilton R. Lustri, Carmen S. P. Lima, Pedro P. Corbi, Raphael E. F. de Paiva   +14 more
wiley   +1 more source

Release and biological performance of theranostics from novel tissue engineering scaffolds for cancer patients

, 2017
For cancer patients, new tissue needs to be formed at the original tumor site after surgery. Scaffold-based tissue engineering can regenerate human body tissues.
Wang, M, Guo, L
core  

The Global Theranostics Access Gap: Real-World Disparities in PSMA PET/CT and ¹⁷⁷Lu-PSMA Therapy Between Centers in Brazil and Europe. [PDF]

J Nucl Med
Cerci JJ, Fanti S, Herrmann K, Rodrigues DF, Leite PHF, Masukawa M, da Silva MM, Fendler WP, Goncalves E Silva A, Sanfelice EN, Ayelet W, Ghetti F, Bascioni A, Estrado Lobato EE, Paez D.   +14 more
europepmc   +1 more source

Transition Metal‐Free C(sp2)─Ge Bond Construction and Downstream Functionalization

European Journal of Organic Chemistry, EarlyView.
Organogermanes combine the advantages of other tetrels such as silicon or tin without their respective downsides in terms of stability and reactivity. This Perspective describes both the transition metal‐free formation of C(sp2)─Ge bonds and the subsequent functionalizative degermylation reactions to access organic compounds of interest.
Baptiste Neil, Maxence Bonnevial, Guillaume Berionni   +2 more
wiley   +1 more source

How should etiology change the classification of the epilepsies? Report from the ILAE 2021–2025 Terminology Commission

Epilepsia, EarlyView.
Abstract The classification of the epilepsies has traditionally relied on clinical and electroencephalographic features. However, advancements in molecular genetics, neuroimaging, and our understanding of epilepsy pathophysiology necessitate a shift toward an etiology‐based approach.
Nicola Specchio, Stéphane Auvin, Francesca Bisulli, Scott Demarest, Elena Gardella, Angelina Kakooza Mwesige, Rima Nabbout, Alshimaa S. Othman, Kollencheri Puthenveettil Vinayan, Robyn Whitney, Elaine Wirrell, Hideo Yamanouchi, Ji Yeoun Yoo, Sameer M. Zuberi, J. Helen Cross, Ingrid E. Scheffer   +15 more
wiley   +1 more source