Results 181 to 190 of about 40,969 (293)

Bismuth-based nanosystems for precise tumor theranostics: Recent progress, challenges and perspectives. [PDF]

open access: yesTheranostics
Zhang H   +10 more
europepmc   +1 more source

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo   +4 more
wiley   +1 more source

Uneven Global Distribution of Theranostics. [PDF]

open access: yesWorld J Nucl Med
Kairemo K, Al-Ibraheem A.
europepmc   +1 more source

Aptamer–Based Targeted Protein Degradation: Mechanistic Principles, Delivery Strategies, and Translational Opportunities

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Targeted elimination of pathogenic proteins remains a fundamental challenge in therapeutic intervention, particularly for proteins considered “undruggable” by conventional inhibition‐based approaches. Aptamer–based targeted protein degradation (TPD) has emerged as a versatile strategy that leverages the high specificity, structural ...
Ambrin Malik   +3 more
wiley   +1 more source

Artificial Intelligence in Nuclear Medicine (2015-2025): Clinical Applications, Regulatory Governance, and Pharmacotherapeutic Implications. [PDF]

open access: yesCureus
Alpizar-Rojas M   +6 more
europepmc   +1 more source

177Lu‐labeled amidoxime‐functionalized biodegradable microspheres for transarterial radioembolization of hepatocellular carcinoma

open access: yesPrecision Radiation Oncology, EarlyView.
Scheme 1. Schematic illustration of the synthesis and therapeutic evaluation of PLA‐g‐PAO microspheres (PLA‐g‐PAO‐Ms). Monodisperse PLA microspheres (PLA‐Ms) were initially fabricated via microfluidic technology. Surface grafting of acrylonitrile monomers was subsequently achieved through radiation‐induced graft polymerization, followed by ...
Xingliang Liu   +7 more
wiley   +1 more source

C–X–C Motif Chemokine Receptor 4 (CXCR4)‐Targeted Biologically Guided Proton Spatially Fractionated Radiotherapy for Bulky Limited‐Stage Small Cell Lung Cancer

open access: yesPrecision Radiation Oncology, EarlyView.
A newly proposed proton spatially fractionated radiotherapy guided by biological imaging Abstract Background and Purpose To evaluate the feasibility and dosimetric safety of integrating C–X–C motif chemokine receptor 4 (CXCR4)‐targeted tracer 18F‐AlF‐NOTA‐QHY‐04 positron emission tomography imaging with biologically guided proton spatially fractionated
Keru Pu   +7 more
wiley   +1 more source

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