Results 71 to 80 of about 59,543 (303)

Nanocrystal Quality–Controlled Scintillation in Porous YAG:Ce Aerogels

Advanced Optical Materials, EarlyView.
High‐temperature thermal treatment of YAG:Ce nanoscintillator aerogels increases light yield under ionizing radiation by up to eightfold without affecting timing performance. Additionally, low‐temperature atmospheric treatments reversibly modify the cerium oxidation state, revealing strong defect sensitivity and offering new strategies to optimize ...
Pavlo Mai, Yannis Cheref, Raphael Marie‐Luce, Frédéric Lerouge, Julien Houel, Gilles Ledoux, Alice Perret, Francesca Cova, Mauro Fasoli, Benoit Sabot, Frédéric Chaput, Christophe Dujardin   +11 more
wiley   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source

Folate-conjugated nanoparticles as a potent therapeutic approach in targeted cancer therapy [PDF]

, 2015
The selective and efficient drug delivery to tumor cells can remarkably improve different cancer therapeutic approaches. There are several nanoparticles (NPs) which can act as a potent drug carrier for cancer therapy.
Bahrami, B., Bakhshaei, P., Ghalamfarsa, G., Hojjat-Farsangi, M., Jadidi-Niaragh, F., Mohammadnia-Afrouzi, M., Sadreddini, S., Yazdani, Y., Yousefi, M.   +8 more
core   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

Salmonella typhimurium co-expressing cytolysin A and hyaluronidase suppresses tumor growth and metastasis

Cell Death Discovery
Recently, various attenuated bacteria have been studied as cancer therapies due to their unique characteristics, which include tumor-targeting bioactivity and immunogenicity.
Khuynh Van Nguyen, Dinh-Huy Nguyen, Hien Thi-Thu Ngo, Sung-Hwan You, So-young Kim, Yeongjin Hong, Jung-Joon Min   +6 more
doaj   +1 more source

Highly Active Cu14 Cluster Precisely Activates Autophagy Inhibitor to Amplify Cuproptosis Immunotherapy

Advanced Science, EarlyView.
An atomically precise Cu14 cluster‐mediated bond scission reaction pioneers the amplification of the antitumor immune response via synergetic cuproptosis‐associated immunogenic cell death induction and in situ autophagy blockade. ABSTRACT Transition metal‐mediated cleavage mechanisms have emerged as an effective means to mitigate the off‐target ...
Qiu‐Xu Zang, Wei‐Tong Chen, Yu‐Ying Shen, Zhao‐Yang Wang, Kai Li, Xueli Zhao, Yanjuan Sang, Xiaoyuan Chen, Shuang‐Quan Zang   +8 more
wiley   +1 more source

Direct estimation of kinetic parametric images for dynamic PET. [PDF]

, 2013
Dynamic positron emission tomography (PET) can monitor spatiotemporal distribution of radiotracer in vivo. The spatiotemporal information can be used to estimate parametric images of radiotracer kinetics that are of physiological and biochemical ...
Qi, Jinyi, Wang, Guobao
core   +1 more source

The Theranostic Genome

Nature Communications
Theranostic drugs represent an emerging path to deliver on the promise of precision medicine. However, bottlenecks remain in characterizing theranostic targets, identifying theranostic lead compounds, and tailoring theranostic drugs. To overcome these bottlenecks, we present the Theranostic Genome, the part of the human genome whose expression can be ...
Xiaoying Xu, Pablo Jané, Vincent Taelman, Eduardo Jané, Rebecca A. Dumont, Yonathan Garama, Francisco Kim, María del Val Gómez, Karim Gariani, Martin A. Walter   +9 more
openaire   +3 more sources

Biomimetic Ru‐Mn Nanozyme with Cascade Catalytic Activity Attenuates Secondary Brain Injury in Intracerebral Hemorrhage

Advanced Science, EarlyView.
Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan, Peng Li, Yue Wang, Xin Qi, Wanyu Wang, Yongzhong Cheng, Huabin Zhang, Xin Hu, Xiang Gao   +8 more
wiley   +1 more source

Bioengineered Textiles and Nonwovens – the convergence of bio-miniaturisation and electroactive conductive polymers for assistive healthcare, portable power and design-led wearable technology [PDF]

, 2009
Today, there is an opportunity to bring together creative design activities to exploit the responsive and adaptive ‘smart’ materials that are a result of rapid development in electro, photo active polymers or OFEDs (organic thin film electronic devices),
Oliver, Raymond, Tillotson, Jennifer, Toomey, Anne   +2 more
core   +3 more sources