Results 141 to 150 of about 5,632,141 (320)
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale+9 more
wiley +1 more source
CERVICAL SPONDYLOSIS: PILOT THERAPEUTIC TRIAL [PDF]
V. L. Steinberg, R. M. Mason
openalex +1 more source
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu+3 more
wiley +1 more source
OPSONINS AND THE PRACTICAL RESULTS OF THERAPEUTIC INOCULATION WITH BACTERIAL VACCINES. [PDF]
G. Webster Ross
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The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld+7 more
wiley +1 more source
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam+2 more
wiley +1 more source
THE PROTECTION OF INTRACELLULAR BRUCELLA AGAINST THERAPEUTIC AGENTS AND THE BACTERICIDAL ACTION OF SERUM [PDF]
James M. Shaffer+2 more
openalex +1 more source
Therapeutic theatre and spontaneity: Goethe and Moreno [PDF]
Moreno noted a similarity between a late 18th Century play by the great German scholar and artist, Goethe, and some elements of psychodrama, which can be substantiated; however, Goethe was not, as Moreno suggested, an early promoter of spontaneity.
Scheiffele, Eberhard
core
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang+8 more
wiley +1 more source