Results 61 to 70 of about 1,637,380 (277)

Protective effects of an Fc-engineered PD-L1 fusion protein in a spontaneous abortion model and a Th17 cell–induced pregnancy loss model

Frontiers in Pharmacology
The binding of programmed death-ligand 1 (PD-L1) with its receptor PD-1 has been proven to negatively regulate immune responses. Here, we assessed the therapeutic effects of Fc-fused PD-L1 protein on foetomaternal tolerance using a murine spontaneous ...
Guangyao Li, Guangyao Li, Guangyao Li, Tiantian Wang, Dan Tan, Yamin Jin, Xuemei Zhou, Hongru Ai, Xinya Zheng, Xiaochen Ren, Shi Hu, Shi Hu, Changhai Lei, Wenyan Fu, Wenyan Fu   +14 more
doaj   +1 more source

The Decriminalisation of Abortion: an Argument for Modernisation [PDF]

, 2015
While abortion is now offered as a routine part of modern NHS-funded reproductive healthcare, the legal framework regulating it remains rooted in the punitive, conservative values of the mid-Victorian era.
Sheldon, Sally
core   +2 more sources

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

Advanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu, Xinkui Liu, Xiaoyan Yu, Qiaoqiao Han, Feifei Shi, Weiwei Song, Lu Liu, Chu Chu, Chenyang Shen, Zhen Zhang, Xia Li   +10 more
wiley   +1 more source

Bowel Perforation Secondary to Illegally Induced Abortion: a Tertiary Hospital Experience in Tanzania. [PDF]

, 2012
Bowel perforation though rarely reported is a serious complication of induced abortion, which is often performed illegally by persons without any medical training in developing countries.
Gilyoma Japhet M, Mabula D Mchembe, Massinde Anthony, Kihunrwa, Albert, Alphonce B Chandika, Gilyoma, Japhet M, Chandika Alphonce B, Chalya, Phillipo L, McHembe, Mabula D, Phillipo L Chalya, Chalya Phillipo L, Kihunrwa Albert, Joseph B Mabula, Mchembe Mabula D, Anthony Massinde, Chandika, Alphonce B, Massinde, Anthony, Albert Kihunrwa, Japhet M Gilyoma, Mabula, Joseph B, Mabula Joseph B   +20 more
core   +1 more source

SAV1 in Cooperation With FKBP52 Participates in Implantation

Advanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao, Yafang Lu, Zhaoyu Jia, Junxiang Ren, Ziyi Ge, Xinyu Liu, Hui Zhao, Zi‐Jiang Chen, Junhao Yan, Wei Wang, Jia Yuan   +10 more
wiley   +1 more source

El Derecho a La Vida y La Constitución

Revista Chilena de Derecho, 2006
El autor sostiene que para la adecuada comprensión del derecho a la vida consagrado en la Constitución de 1980 es necesario entenderlo como un derecho natural y obra de Dios, que se tiene por el solo hecho de ser persona, y que consiste en el derecho de ...
José Joaquín Ugarte Godoy
doaj  

The Polish Parliament and the making of politics through abortion : nation, gender and democracy in the 1996 Liberalization Amendment Debate [PDF]

, 2009
The collapse of communism across East Central Europe was marked by a renewal of debates around reproduction, with abortion debates surfacing in Romania, Germany and Poland.
Kramer, Anne-Marie, Anne-Marie Kramer, Kramer, Anne-Marie Caroline   +2 more
core   +1 more source

Causal analysis of trade loss from pathogens: A global study of foot and mouth disease impacts on meat exports

American Journal of Agricultural Economics, EarlyView.
Abstract Our general interest is in global trade loss from livestock pathogens, specifically exports. We adopt a causal inference approach that considers animal disease outbreaks over time as non‐staggered binary treatments with the potential for switching in (infection) and out of treatment (recovery) within the sample period. The outcome evolution of
Mohammad Maksudur Rahman, Thomas L. Marsh   +1 more
wiley   +1 more source

Towards a Framework for the Analysis of Abortion Culture

, 2005
What is 'abortion culture'? Whenever family planning in former Soviet states is discussed it is almost inevitable that the phrase ‘abortion culture’ will be used to describe the context within which fertility was, and to an extent still is, controlled in
Grant, Gail
core   +1 more source