Results 41 to 50 of about 74,528 (292)

The digital therapeutic alliance: Prospects and considerations [PDF]

open access: yes, 2021
The growing prevalence of digital approaches to mental health care raises a range of questions and considerations. A notion that has recently emerged is that of the digital therapeutic alliance, prompting consideration of whether and how the concept of ...
D'Alfonso, S, Lederman, R
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Speaking about therapists Old questions and some answers derived from empirical evidence

open access: yesResearch in Psychotherapy, 2011
The paper presents a review of the therapist's role and characteristics with reference to issues regarding general and specific training, theoretical and personal background, the capacity to initiate and maintain therapeutic alliance, the setting ...
Santo Di Nuovo
doaj   +1 more source

Understanding the secondary system of therapeutic alliance in autism interventions from the perspectives of parents and caregivers

open access: yesInternational Journal of Child Care and Education Policy, 2022
This study utilized a sequential explanatory mixed-methods design in understanding the secondary system of therapeutic alliance from the perspectives of parents and caregivers of children with autism. In the quantitative phase, data from the accomplished
John Robert C. Rilveria
doaj   +1 more source

Harnessing the potential of the therapeutic alliance [PDF]

open access: yesWorld Psychiatry, 2014
Originally developed within psychoanalytic psychotherapy, the therapeutic alliance has emerged as a widely studied pantheoretical change variable. In fact, a Google Scholar search for “therapeutic alliance” and “outcome” returns roughly 135,000 hits.
Bruce A, Arnow, Dana, Steidtmann
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

The impact of the therapeutic alliance on treatment outcome in patients with dissociative disorders [PDF]

open access: yesEuropean Journal of Psychotraumatology, 2014
Background: Research has shown that the therapeutic alliance plays an important role in enhancing treatment outcome among individuals with a variety of disorders, including posttraumatic stress disorder (PTSD).
Elisabeth Cronin   +2 more
doaj   +1 more source

Digital therapeutic alliance in psycho-oncology: an overview

open access: yesPsicosomática y Psiquiatría, 2022
Introduction: After the declaration of the COVID-19 pandemic, health services have had to adapt to be delivered by eHealth tools. Cancer population has extensively experienced this disruption due to non-urgent in-person visits being deferred to avoid ...
A. Flix-Valle   +4 more
doaj   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler   +20 more
wiley   +1 more source

The subjective experience of psychotherapists during moments of rupture in psychotherapy with adolescents

open access: yesResearch in Psychotherapy, 2019
The study of the ruptures of the therapeutic alliance has impacted research in psychotherapy by highlighting the relational nature of this phenomenon.
Javier Morán   +4 more
doaj   +1 more source

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