Results 241 to 250 of about 2,615,972 (289)

TREX1, a predator for treating MSI‐H tumors?

open access: yesMolecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya   +2 more
wiley   +1 more source

Ibrutinib-Associated Liver Injury in a Patient with Chronic Lymphocytic Leukemia: Clinical Course and Therapeutic Approach. [PDF]

open access: yesHematol Rep
Frolli A   +7 more
europepmc   +1 more source

Sigmoid Volvulus in Children: A Structured Diagnostic and Therapeutic Approach. [PDF]

open access: yesPediatr Gastroenterol Hepatol Nutr
Dmytro K, Ivana S, Lubomir M, Peter I.
europepmc   +1 more source

Buschke-Löwenstein Tumor: An Unusual Therapeutic Approach. [PDF]

open access: yesGE Port J Gastroenterol
Gonçalves R   +5 more
europepmc   +1 more source

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