Results 231 to 240 of about 6,648,309 (299)

Mechanisms of Impaired Skeletal Muscle Regeneration and Therapeutic Approaches in Aging and Chronic Disease. [PDF]

Pharmaceuticals (Basel)
Li X, Zhao Z, Yang J, Zhang Y, Yao X, Sun H, Shen Y.   +6 more
europepmc   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Methanol intoxication and acute kidney injury: pathophysiological mechanisms and therapeutic approaches. [PDF]

J Bras Nefrol
Nogueira GN, Teles CBM, Varão MVS, Costa AC, Ramos GML, Daher EF.   +5 more
europepmc   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Cardiologists' Diagnostic and Therapeutic Approaches in the Outpatient Management of Patients with Chronic Coronary Syndrome in Turkey: An Observational-Registration Study. [PDF]

J Cardiovasc Dev Dis
Arslan A, Ozkaya OG, Aytemiz F, Küçükukur M, Asiltürk E, Iyigün U, Bayram M, Fedai H, Koç Ş, Malkoç D, Doğduş M, Kümet Ö, Bayrak M, Öztürk Ö, Koçak A, Ömür SE, Bekar L, Kayhan Ö, Katkat F, Öztürk C, Yeşil E, Akgümüş A, Balun A, Erdoğan A, Kunak AÜ, Toprak K, Er F, Serin E, Çalışkan S, İnci S, Zoghi M.   +30 more
europepmc   +1 more source

Corrigendum to "Modern therapeutic approaches in cholangiocarcinoma: A narrative review of key biomarkers and clinical trials" [Translational Oncology 72 (2026) 103005]. [PDF]

Transl Oncol
Almeida A, Manzi J, Hoff C, Kadri H, Ferreira R, Livingstone A, Gleisner A, Toegel EB, Schulick R, Hoff PM, Vianna R, Abreu P.   +11 more
europepmc   +1 more source

Correction to "Psychosocial Interventions for Substance Use Disorder: A Systematic Review of Therapeutic Approaches and Their Clinical Effectiveness". [PDF]

Clin Psychol Psychother
europepmc   +1 more source