Results 141 to 150 of about 678,102 (350)
Concepts for the Rational Selection of Assays to Be Used in Monitoring Therapeutic Drugs [PDF]
, 1975 Mario Werner +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda +3 more
wiley +1 more source
Vedolizumab trough level monitoring in inflammatory bowel disease: a state-of-the-art overview
BMC Medicine, 2019 Background Therapeutic drug monitoring involves therapeutic modifications based on the measurement of drug levels and antidrug antibodies. The viability of therapeutic drug monitoring in vedolizumab-treated patients with inflammatory bowel disease ...
Lieven Pouillon +2 more
doaj +1 more source
Electrochemical biosensors: a nexus for precision medicine [PDF]
, 2021 Precision medicine is a field with huge potential for improving a patient's quality of life, wherein therapeutic drug monitoring (TDM) can provide actionable insights.
Basit, AW +6 more
core
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
A Two-Layer Mathematical Modelling of Drug Delivery to Biological Tissues [PDF]
arXiv, 2016 Local drug delivery has received much recognition in recent years, yet it is still unpredictable how drug efficacy depends on physicochemical properties and delivery kinetics. The purpose of the current study is to provide a useful mathematical model for drug release from a drug delivery device and consecutive drug transport in biological tissue ...
arxiv
Technical considerations in the use of "high-performance" liquid chromatography in therapeutic drug monitoring. [PDF]
, 1983 Roger W. Giese
openalex +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
wiley +1 more source
A possible interaction between linezolid and digoxin: A case report of therapeutic drug monitoring
Saudi Pharmaceutical Journal, 2020 Drug-drug interactions lead to altered clinical effects, including adverse reactions. Therapeutic drug monitoring of digoxin is necessary due to its narrow therapeutic range.
Zhu Yulin +3 more
doaj